Effect of multimodal opioid-sparing anesthesia on intestinal function and prognosis of elderly patients with hypertension after colorectal cancer surgery

Effect of Opioid-Sparing Anesthesia on Recovery in Elderly Patients After Colorectal Surgery

Purpose

The study focuses on how a specific type of anesthesia affects the recovery of elderly patients with hypertension who undergo surgery for colorectal cancer (CRC). It looks to improve recovery outcomes and reduce complications.

Methods

Researchers studied 80 elderly patients with hypertension who had CRC surgery. They divided the patients into two groups:

  • Group A: Received multimodal opioid-sparing anesthesia, which included low-dose opioids combined with additional pain management techniques.
  • Group B: Received conventional opioid anesthesia, utilizing standard dosages of remifentanil.

The study measured various outcomes, such as recovery times for bowel function and pain levels, as well as the overall hospital stay duration.

Results

Out of the initial participants, 72 were analyzed. Key findings include:

  • Group A had faster recovery times for bowel sounds and first bowel movements.
  • They also showed better postoperative health indicators, with higher albumin and lower CRP and WBC levels.
  • The incidence of nausea and vomiting was lower in Group A.
  • Group A had shorter total hospital stays compared to Group B.

Conclusion

Using multimodal opioid-sparing anesthesia helps elderly patients recover intestinal function more quickly and reduces unpleasant side effects after surgery. This method is safe and practical for older patients with hypertension undergoing CRC surgery.

Value of Clinical Trials

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