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Objective
This research looked at how different types of hemodialysis, when combined with low-calcium dialysate (LCD), affect mineral balance and blood vessel hardening in patients with chronic kidney disease (CKD) who are on maintenance hemodialysis (MHD).
Methods
Data was gathered from 192 MHD patients, who were divided into four groups. Each group received LCD treatment along with one of the following hemodialysis methods: conventional hemodialysis (HD), high-flux HD (HFHD), hemodiafiltration (HDF), or HD with hemoperfusion (HP). Treatments were done three times a week for four hours over six months. Blood samples were taken to measure various health markers, and CT scans were used to check for calcification in blood vessels.
Results
After treatment, levels of inflammation and mineral balance improved in all groups. The HD + HP group showed the greatest improvements, followed by HDF and HFHD groups. The rates of vascular calcification were lower in the HDF, HFHD, and HD + HP groups compared to the HD group, with the HD + HP group having the best results.
Conclusion
Using HD + HP along with LCD is effective for CKD patients on MHD. It helps correct mineral imbalances, improves kidney function, reduces inflammation, and lowers the risk of vascular calcification.
Opportunities for Clinics and Patients
Based on the trial data, clinics can set clear goals for improving patient outcomes by implementing the HD + HP method with LCD. Measurable outcomes include better mineral balance, reduced inflammation, and lower vascular calcification rates.
AI Tools for Clinical Needs
Select AI solutions that are specifically designed to track and improve these health outcomes in hemodialysis patients.
Implementation Plan
Start with a pilot project to test these methods, using AI tools to track results and assess their real-world impact on patient health.
Contact Us for AI Solutions
If you are interested in AI solutions for medical management, please reach out to us:
- Telegram: https://t.me/itinai
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