Effects of inhaled beclometasone dipropionate/formoterol fumarate/glycopyrronium vs. beclometasone dipropionate/formoterol fumarate and placebo on lung hyperinflation and exercise endurance in chronic obstructive pulmonary disease: a randomised controlled trial

Effects of Inhaled Beclometasone Dipropionate/Formoterol Fumarate/Glycopyrronium in COPD

Study Overview

This study investigated the effects of a single inhaler containing beclometasone dipropionate, formoterol fumarate, and glycopyrronium (BDP/FF/G) on lung hyperinflation and exercise endurance in patients with chronic obstructive pulmonary disease (COPD).

Key Findings

  • Participants: 106 adults with COPD were enrolled; 95 completed the study.
  • Improvement in Lung Capacity: BDP/FF/G showed a significant increase in resting inspiratory capacity (IC) compared to placebo (315 mL) and BDP/FF (223 mL).
  • Dynamic Lung Capacity: BDP/FF/G improved dynamic IC by 245 mL compared to placebo.
  • Exercise Endurance: Patients using BDP/FF/G had an increase in exercise endurance time by 69.2 seconds compared to placebo.
  • Tolerability: All treatments were well tolerated, with mild to moderate adverse events reported.

Practical Solutions and Value

BDP/FF/G provides significant benefits for patients with COPD, enhancing both lung function and exercise capacity. This can lead to improved quality of life for those affected by this condition.

Clinical Implementation

To maximize the benefits of clinical trials, tools like DocSym can help integrate research findings into everyday practice. This AI-driven platform consolidates clinical guidelines and protocols, making it easier for healthcare providers to access vital information.

Streamlined Patient Care

Our mobile applications facilitate scheduling, monitoring treatments, and telemedicine, enhancing patient management and expanding digital services. By leveraging AI, clinics can improve workflows, reduce paperwork, and ultimately enhance patient outcomes.

Learn More

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