Effects of low-intensity pulsed ultrasound on clinical parameters in atherosclerotic peripheral artery disease patients with chronic limb-threatening ischemia

Overview of Chronic Limb-Threatening Ischemia (CLTI)

Chronic limb-threatening ischemia (CLTI) is a serious health issue affecting patients with poor blood flow in their legs. It can lead to significant pain and mobility challenges.

What is Low-Intensity Pulsed Ultrasound (LIPUS)?

Low-intensity pulsed ultrasound (LIPUS) is a non-invasive treatment that has been found to help improve conditions in patients suffering from CLTI.

Study Findings

A recent study involved 37 patients with severe atherosclerotic peripheral artery disease who were not candidates for standard surgery. They received LIPUS treatment for 20 minutes every day for 12 weeks. Here are the key results:

  • Rest pain intensity decreased significantly.
  • Walking ability improved, as measured by a questionnaire.
  • Blood flow to the skin (skin perfusion pressure) showed significant improvement.
  • Vascular health (flow-mediated vasodilation) improved.
  • Inflammation markers decreased.
  • No patients experienced adverse effects from the treatment.

Long-Term Outcomes

After an average follow-up of over 7 years, the survival rate was about 89%, and limb survival was also around 89% at one year. This indicates that LIPUS may provide lasting benefits for patients with CLTI.

Practical Solutions for Clinics

Define Measurable Outcomes

Clinics should aim to track improvements in pain levels, walking ability, and blood flow in patients undergoing LIPUS treatment.

Select Appropriate AI Tools

Choose AI solutions that match clinical needs, such as monitoring patient progress or analyzing treatment effectiveness.

Implement Step-by-Step

Start with a pilot program using LIPUS, track the outcomes, and adapt based on results to improve patient care.

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