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Background
Oral mucositis (OM) is a painful condition that many children face when undergoing chemotherapy. This clinical trial tested two treatments: photobiomodulation (PBM) to prevent OM and photodynamic therapy (PDT) to treat it in children with blood cancers.
Methods
In the prevention phase, some patients did not receive PBM initially but were given it in their next treatment cycle, allowing for a fair comparison. In the treatment phase, patients with OM were randomly assigned to either a control group (no real treatment) or a PDT group.
Results
For prevention, PBM significantly reduced the occurrence of OM from 66.67% to 6.67%. In the treatment phase, patients receiving PDT showed better improvement in OM symptoms compared to those in the control group, with significant reductions in pain and discomfort measured at 3 and 5 days after starting treatment.
Conclusion
PBM is a safe and effective way to prevent OM in children undergoing chemotherapy. PDT also shows promise in treating OM lesions. These findings suggest that PBM can help manage OM effectively in pediatric patients.
Opportunities for Clinics and Patients
Based on the trial data, clinics can:
- Set clear goals for using PBM to prevent OM.
- Measure outcomes such as the reduction in OM incidence and symptom severity.
- Implement PBM and PDT in treatment plans for pediatric patients.
AI Tools for Clinical Needs
Clinics can select AI solutions that fit their specific needs, such as:
- Tracking patient outcomes.
- Analyzing treatment effectiveness.
Implementation Steps
Start with a pilot project using PBM and PDT, track results, and assess the real-world impact of these treatments on patients.
Contact Us
For AI solutions in medical management, reach out to us:
- Telegram: https://t.me/itinai
- X: https://x.com/vlruso
- LinkedIn: https://www.linkedin.com/company/itinai/
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