Conditions: Rectal Cancer
Interventions: Procedure: Flexible colonoscope assisted hybrid transanal total mesorectal resection
Sponsors: Sun Yat-sen University
Recruiting
Flexible Colonoscope Assisted Hybrid Transanal Total Mesorectal Resection (taTME)
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Clinical Research
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Effectiveness of a self-help guide during a temporary alcohol abstinence challenge: a randomized controlled trial
Effectiveness of a Self-Help Guide for Alcohol Abstinence Key Findings The study aimed to assess the impact of a self-help guide on successful completion of a temporary alcohol abstinence challenge…
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Exercise-Induced Oxygen Desaturation Increases Arterial Stiffness in Patients with COPD During the 6WMT
Exercise-Induced Oxygen Desaturation and Arterial Stiffness in COPD Patients Study Overview This study aimed to investigate the impact of exercise-induced oxygen desaturation (EID) on arterial stiffness in individuals with COPD.…
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Protocol for a multicentric, double-blind, randomised controlled trial of hyperbaric oxygen therapy (HBOT) versus sham for treating vaso-occlusive crisis (VOC) in sickle cell disease (SCD) in patients aged 8 years or older (HBOT-SCD study)
Protocol Overview Study Title: Hyperbaric Oxygen Therapy (HBOT) for Treating Vaso-Occlusive Crisis (VOC) in Sickle Cell Disease (SCD) Publication: BMJ Open, November 2024 Introduction Sickle cell disease (SCD) is a…
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Brief intensive EMDR therapy for PTSD in adults with mild intellectual disability or borderline intellectual functioning and behavioural problems: a multiple baseline design study
Background People with mild intellectual disability (MID) or borderline intellectual functioning (BIF) often face higher risks of developing post-traumatic stress disorder (PTSD). This can lead to various behavioral issues. It’s…
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Molecular monitoring versus standard clinical care in younger adults with acute myeloid leukaemia: results from the UK NCRI AML17 and AML19 randomised, controlled, phase 3 trials
Background In patients with acute myeloid leukaemia (AML), finding measurable residual disease (MRD) usually means a poor outlook. This study looked at whether changing treatment based on MRD results could…
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Solving unknown primary cancer with earlier diagnosis — the SUPER-ED trial: study protocol for a stepped-wedge cluster randomised controlled trial to support earlier diagnosis for people presenting with malignancy of undefined primary origin
Addressing Unknown Primary Cancer with Early Diagnosis — The SUPER-ED Trial Background Patients with malignancy of undefined origin (MUO) face serious challenges, including poor outcomes and lengthy diagnostic processes. This…
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Are Dutch adults equally susceptible to nudging and pricing strategies? Secondary analyses of the Supreme Nudge parallel cluster-randomised controlled supermarket trial
Are Dutch Adults Equally Susceptible to Nudging and Pricing Strategies for Healthier Diets? Practical Findings from the Supreme Nudge Supermarket Trial Supermarket interventions aimed at promoting healthier dietary patterns were…
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Text Messaging Versus Postal Reminders to Improve Participation in a Colorectal Cancer Screening Program: Randomized Controlled Trial
Text Messaging Versus Postal Reminders for Colorectal Cancer Screening Study Overview This study compared the effectiveness of SMS text message reminders to traditional postal reminders for increasing participation in a…
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Usability and acceptability of ambulatory monitoring in undiagnosed syncope: insights from the ASPIRED-Q qualitative study
Study Overview This study, part of the ASPIRED trial, looked at how patients and healthcare professionals felt about using a new 14-day ECG monitoring patch for patients in the emergency…
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Rapid respiratory microbiological point-of-care-testing and antibiotic prescribing in primary care: Protocol for the RAPID-TEST randomised controlled trial
Protocol for the RAPID-TEST Randomised Controlled Trial Introduction In primary care, antibiotics are often prescribed for respiratory infections without clear benefit, leading to microbial resistance. Point-of-care-tests can provide rapid microbiological…
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A 2.6% Benzoyl Peroxide AV Cleanser Specifically Designed for Sensitive Skin Offers Good Efficacy and Tolerability
Study Highlights: 2.6% Benzoyl Peroxide AV Cleanser for Sensitive Skin Effective and Well-Tolerated Treatment for Acne Vulgaris A clinical study evaluated the efficacy and safety of a 2.6% Benzoyl Peroxide…
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Streamlined Genetic Education and Cascade Testing in Men from Hereditary Breast Ovarian Cancer Families: A Randomized Trial
Streamlined Genetic Education and Cascade Testing in Hereditary Cancer Families: Key Findings Introduction When a pathogenic BRCA1 or BRCA2 mutation is found in a family, it is important for family…
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The State of Intermediate Clinical Endpoints as Surrogates for Overall Survival in Prostate Cancer in 2024
“`html Summary of Clinical Trial Findings Recent research in prostate cancer trials has focused on finding intermediate clinical endpoints (ICEs) that can provide reliable indicators of overall survival (OS). Practical…
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Improving Progression-Free Survival in Platinum-Sensitive Ovarian Cancer: Insights from the SOLACE2 Trial
Understanding the SOLACE2 Trial Results The SOLACE2 trial looked at how well different treatments work for women with platinum-sensitive recurrent ovarian cancer. The main goal was to see if a…
