Flow-S: A Field-Deployable Device with Minimal Hands-On Effort to Concentrate and Quantify Schistosoma Circulating Anodic Antigen (CAA) from Large Urine Volumes

The Flow-S Device: A Practical Solution for Field-Based Diagnosis of Schistosoma Infection

Background:

– A new device called Flow-S has been developed to simplify the diagnosis of active Schistosoma infection in the field using urine samples.
– Current laboratory-based tests for this infection require complex pre-treatment steps that are not suitable for field use.

Key Findings:

– The prototype Flow-S device showed promising results in identifying active Schistosoma infection using urine samples.
– It integrates large-volume urine concentration and detection into a single field-deployable device, omitting the need for laboratory-based pre-treatment steps.

Value and Practical Applications:

– The Flow-S device can replace the urine pre-treatment required for existing laboratory-based tests, making it suitable for true field-based applications with fresh urine samples.
– It has potential for testing pooled urine samples, making it applicable for population stratified testing.
– Further optimization and testing with larger sample sizes are planned for the Flow-S device to enhance its efficacy in field settings.

Published in Diagnostics (Basel) | PMID:38667466 | DOI:10.3390/diagnostics14080820

Full research Flow-S: A Field-Deployable Device with Minimal Hands-On Effort to Concentrate and Quantify Schistosoma Circulating Anodic Antigen (CAA) from Large Urine Volumes: https://pubmed.ncbi.nlm.nih.gov/38667466/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=1B1L42DK3a-JWCV4P_PtHHBmWjwBLFNcDXsYJkbqjQD0Ca7UQh&fc=None&ff=20240426163055&v=2.18.0.post9+e462414

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