Conditions: Type 1 Diabetes Mellitus; Type 1 Diabetes Mellitus With Hypoglycemia; Drive
Interventions: Device: MiniMed 780 G
Sponsors: University Hospital, Motol
Not yet recruiting
Glycemic Excursions in Patients With Type 1 Diabetes Mellitus Using Closed-loop Systems
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Clinical Research
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KHK2455 and Mogamulizumab: Promising Combination Therapy for Advanced Solid Tumors
Trial Overview This trial tested a new treatment called KHK2455, both alone and with another drug, mogamulizumab, in patients with advanced solid tumors that did not respond to other treatments.…
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A systems analysis and improvement approach to optimizing syringe services programs’ delivery of HIV testing and referrals: Study protocol for a parallel-group randomized controlled trial (SAIA-SSP-HIV)
Background HIV transmission has risen in the U.S. among people who inject drugs. Testing for HIV and connecting individuals to treatment is essential for both personal and public health. However,…
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An eHealth Intervention to Improve Quality of Life, Socioemotional, and Health-Related Measures Among Older Adults With Multiple Chronic Conditions: Randomized Controlled Trial
An eHealth Intervention to Improve Quality of Life for Older Adults Background In the U.S., over 60% of adults aged 65 and older have multiple chronic health conditions. This leads…
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Clinical Evaluation of the Effect of Aficamten on QT/QTc Interval in Healthy Participants
Study Overview Aficamten is a new medication being tested to treat hypertrophic cardiomyopathy (HCM), a condition that affects the heart. This study looked at how aficamten affects the QTc interval,…
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Clinical effect of MB-PDT assisted initial therapy on alveolar angle absorption of lower anterior teeth
Clinical Effect of MB-PDT Assisted Initial Therapy on Alveolar Angle Absorption of Lower Anterior Teeth Abstract Purpose: To assess the impact of MB-PDT assisted essential therapy on angle resorption of…
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The Renewing Intimacy and SExuality Intervention for Female Cancer Survivors: A Feasibility Study
The Renewing Intimacy and Sexuality Intervention for Female Cancer Survivors: A Feasibility Study Purpose: This study looked into a three-session program aimed at helping women with breast and gynecologic cancer…
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Assessing the impact of a self-guided digital intervention for fear of cancer recurrence (iConquerFear) in ovarian cancer survivors: a pilot randomised waitlist-controlled trial
Background About half of ovarian cancer survivors experience a strong fear of their cancer coming back, which makes it hard for them to cope with life after treatment. This study…
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Effectiveness of osteopathic treatment in women with primary dysmenorrhea: A randomised controlled trial
Effectiveness of Osteopathic Treatments for Menstrual Pain This study focused on the effectiveness of five osteopathic treatments for women suffering from primary dysmenorrhea, which is severe menstrual pain. Conducted in…
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Molecular monitoring versus standard clinical care in younger adults with acute myeloid leukaemia: results from the UK NCRI AML17 and AML19 randomised, controlled, phase 3 trials
Background In patients with acute myeloid leukaemia (AML), finding measurable residual disease (MRD) usually means a poor outlook. This study looked at whether changing treatment based on MRD results could…
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“Oral Butyrate for Metabolic Dysfunction-Associated Steatotic Liver Disease: Key Insights for Healthcare Professionals”
Understanding the Study Results This study looked at how two different forms of butyrate, a substance that may help liver health, affect patients with a condition known as metabolic dysfunction-associated…
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Improving Care for Unhealthy Alcohol Use: Results from the Facilitating Alcohol Screening and Treatment (FAST) Colorado Study
Unhealthy Alcohol Use and Its Impact Unhealthy alcohol use (UAU) leads to significant health issues and more than 140,000 deaths annually in the US. Routine screening for UAU in adults…
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Check your HbA1c: AI tells you what it means and what to change
Understanding Your HbA1c Chatbot: A Tool for Smarter Health Choices Your HbA1c test result is more than a number—it’s a window into your long-term blood sugar management. But interpreting what…
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Effects of monitoring dietary biomarkers and providing vegetable juice on metabolic syndrome components in adults with an overweight or obese body mass index in Ulaanbaatar: a randomized controlled trial
Effects of Monitoring Dietary Biomarkers and Providing Vegetable Juice on Metabolic Syndrome in Overweight Adults Background Mongolian people often do not eat enough vegetables, leading to more cases of metabolic…
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Reduced-dose chemotherapy and blinatumomab as induction treatment for newly diagnosed Ph-negative B-cell precursor acute lymphoblastic leukemia: a phase 2 trial
Reduced-dose chemotherapy and blinatumomab as induction treatment for newly diagnosed Ph-negative B-cell precursor acute lymphoblastic leukemia: a phase 2 trial Abstract Blinatumomab has shown promise in improving the initial treatment…
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Effectiveness of a Web-Based Cognitive Behavioral Self-Help Intervention for Binge Eating Disorder: A Randomized Clinical Trial
Effectiveness of a Web-Based Cognitive Behavioral Self-Help Intervention for Binge Eating Disorder: A Randomized Clinical Trial Abstract Importance: Binge eating disorder (BED) causes significant emotional and physical distress, but access…
