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Insights on Corneal Neurotization for Neurotrophic Keratopathy
Practical Solutions and Value
- Neurotrophic keratopathy (NK) results from corneal denervation due to various trigeminal nerve dysfunctions.
- Modern corneal neurotization (CN) techniques aim to restore corneal sensitivity with less invasive options.
- Donor nerve selection and preparation are crucial for surgical success and often require multidisciplinary teams.
- Key donor nerves for CN include the supratrochlear (STN), supraorbital (SON), and great auricular (GAN) nerves.
- Graft options include the sural (SN), lateral antebrachial cutaneous nerve (LABCN), and allografts from cadavers.
- Factors influencing surgical outcomes, such as nerve caliber matching and axonal regeneration, are significant.
- Future directions focus on less invasive techniques and the potential of acellular nerve allografts.
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