Long-Term Effect of Home Blood Pressure Self-Monitoring Plus Medication Self-Titration for Patients With Hypertension: A Secondary Analysis of the ADAMPA Randomized Clinical Trial

Long-Term Effect of Home Blood Pressure Self-Monitoring Plus Medication Self-Titration for Patients With Hypertension: A Secondary Analysis of the ADAMPA Randomized Clinical Trial

Summary:

BP self-monitoring and self-titration of antihypertensive medication, in combination with primary-care nursing involvement, were found to effectively lower blood pressure in the longer term without increasing health care use or adverse events. This suggests that simple, inexpensive, and easy-to-implement self-management interventions have the potential to improve the long-term control of hypertension in routine clinical practice.

Key findings:

  • The adjusted mean difference in systolic blood pressure (SBP) at 24 months was -3.4 mm Hg (P < .001).
  • The adjusted mean difference in diastolic blood pressure (DBP) at 24 months was -2.5 mm Hg (P < .001).
  • No differences were observed between groups in behaviors, quality of life, use of health services, or adverse events.

Value and Practical Solutions:

Results from this study highlight the potential of home blood pressure self-monitoring and medication self-titration as a practical, cost-effective, and easily implementable approach to improving long-term hypertension control in everyday clinical practice.

TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT03242785

PMID: 38728033 | DOI: 10.1001/jamanetworkopen.2024.10063

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