Modulation of Hormonal, Metabolic, and Inflammatory Biomarkers in Women with PCOS
Study Overview
Polycystic Ovary Syndrome (PCOS) is a common condition among women. Exercise is known to help, but there’s limited research on the best types of exercise. This study looked at how combined training (both resistance and endurance) affects various health markers in women with PCOS.
Methodology
We conducted a randomized controlled trial with 30 women aged around 24 years, who were divided into two groups. One group participated in a combined training program for eight weeks, while the other group did not. We measured several health indicators before and after the training, including:
- Fasting plasma glucose
- Insulin levels
- Cholesterol levels
- Hormones like testosterone and AMH
- Markers of oxidative stress and inflammation
Key Findings
After eight weeks of training, the group that exercised showed significant improvements:
- Reduced insulin levels
- Lower cholesterol and testosterone levels
- Improved insulin sensitivity
However, other health markers did not show significant changes compared to the control group.
Conclusions
Combined training is an effective way to help manage PCOS symptoms. The recommended training intensity is 50%-70% of one-repetition maximum for strength and 60%-70% of target heart rate for endurance. More research is needed to optimize exercise protocols for PCOS patients.
Trial Registration
This trial is registered in the Iranian Registry of Clinical Trials (IRCT20130812014333N143). You can access it here.
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