Optical Molecular Imaging in Oral and Oropharyngeal Cancer
Study Overview
This study focuses on a new imaging agent, FG001, designed to improve the detection of oral and oropharyngeal squamous cell carcinoma (OSCC, OPSCC) during surgery. Accurate identification of cancerous tissue is crucial for better patient outcomes.
Trial Details
We conducted a phase II clinical trial to evaluate FG001’s effectiveness in identifying tumors. The trial involved:
- Participants: 16 patients undergoing surgery.
- Dosage: Patients received varying doses of FG001 before surgery.
- Monitoring: Close safety checks were performed throughout the trial.
Results
Key findings include:
- Detection Success: FG001 identified all tumors with 100% sensitivity.
- Imaging Quality: The average tumor-to-background ratio was 2.99.
- Safety: No serious side effects were reported.
Conclusion
FG001 shows promise for enhancing tumor detection during surgery. Further research is needed to explore its use in defining surgical margins and aiding clinical decisions.
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