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Phase 1 Study of MK-5475, an Inhaled Soluble Guanylate Cyclase Stimulator, in Participants with Pulmonary Hypertension Associated with Chronic Obstructive Pulmonary Disease

Phase 1 Study of MK-5475 for Pulmonary Hypertension in COPD Patients

Key Findings:

This study assessed the safety and effectiveness of MK-5475 in COPD patients with pulmonary hypertension. The results showed a favorable safety profile and numerical reductions in pulmonary vascular resistance, supporting further development of MK-5475 for PH-COPD treatment.

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