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Itinai.com stem cells therapy chaos 50 stylize 500 weir ebdc9192 9a23 4da2 aa35 12e91fb2f4b3 0

Phase 1 Study of MK-5475, an Inhaled Soluble Guanylate Cyclase Stimulator, in Participants with Pulmonary Hypertension Associated with Chronic Obstructive Pulmonary Disease

Phase 1 Study of MK-5475 for Pulmonary Hypertension in COPD Patients

Key Findings:

This study assessed the safety and effectiveness of MK-5475 in COPD patients with pulmonary hypertension. The results showed a favorable safety profile and numerical reductions in pulmonary vascular resistance, supporting further development of MK-5475 for PH-COPD treatment.

Practical Solutions and Value:

Clinical trials are essential for developing safe and effective treatments. Our AI-driven platform, DocSym, consolidates standards, protocols, and research into an easily accessible knowledge base for clinicians, helping to extend the benefits of clinical trials into everyday medical practice.

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Clinical Research

2025-01-14

Clinical trials

Improving the accUracy of Referrals to the emerGency departmEnt of patieNts with chesT pain using the modified HEART score in Emergency Medical Transport (URGENT 2.0): protocol for a multicentre randomised controlled trial

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2025-01-07

Clinical trials

Atezolizumab plus bevacizumab in patients with unresectable or metastatic mucosal melanoma: 3-year survival update and multi-omics analysis

Atezolizumab and Bevacizumab for Mucosal Melanoma: Key Findings Background Atezolizumab combined with bevacizumab has shown promising results for patients with advanced mucosal melanoma. This report updates the survival rates over…
2024-05-17

Clinical trials

Validity of remote live stream video evaluation of the North Star Ambulatory Assessment in patients with Duchenne muscular dystrophy

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2025-04-22

Clinical trials

Association Between Plasma Amyloid-Beta 42 Ratio and Postoperative Delirium in Elderly Patients Undergoing Major Abdominal Surgery: Secondary Analysis of a Randomized Controlled Trial

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2024-09-27

Clinical trials

Study protocol for writing to heal: A culturally based brief expressive writing intervention for Chinese immigrant breast cancer survivors

Study Protocol: Culturally Based Writing Intervention for Chinese Immigrant Breast Cancer Survivors Practical Solutions and Value This study aims to test the health benefits of expressive writing tailored for Chinese…
2025-03-20

Clinical trials

Effect of photobiomodulation and selective caries removal in deep cavities on postoperative sensitivity, pulp vitality and dentin neoformation: randomized clinical trial and tomographic evaluation

Clinical Trial Summary Study Overview This clinical trial looked at how selective caries removal in deep cavities affects tooth sensitivity, pulp health, and new dentin formation. The study also examined…
2024-05-21

Clinical trials

Rapid respiratory microbiological point-of-care-testing and antibiotic prescribing in primary care: Protocol for the RAPID-TEST randomised controlled trial

Protocol for the RAPID-TEST Randomised Controlled Trial Introduction In primary care, antibiotics are often prescribed for respiratory infections without clear benefit, leading to microbial resistance. Point-of-care-tests can provide rapid microbiological…
2025-06-06

Clinical trials

Improving Asthma Management in Children: Understanding Therapy Adherence and Inhalation Technique

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2024-07-23

Clinical trials

A randomized translational study on protein- and glucose metabolism in skeletal muscles evaluated by gene-ontology, following preoperative oral carbohydrate loading compared to overnight peripheral parenteral nutrition (PPN) before major cancer surgery

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2024-04-24

Cancer

The Clinical Study of SHR-7631 for Injection in Patients With Advanced Solid Tumors
2025-02-05

Clinical trials

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Comparison of Vitagnus, Soy, and Vitagnus-Soy Capsules for Premenstrual Syndrome Background Premenstrual syndrome (PMS) affects many women and can lower their quality of life. This study looked at how effective…
2025-01-09

Clinical trials

Technology and Dementia Preconference

Technology and Dementia Preconference Background Alzheimer’s disease (AD) is a major global health issue that requires new treatment methods. Recent advancements in medical devices using biophoton technology have shown promise…
2025-05-15

Clinical trials

Anaerobutyricum soehngenii improves glycemic control and other markers of cardio-metabolic health in adults at risk of type 2 diabetes

Study Overview Anaerobutyricum soehngenii, a safe and beneficial gut microbe, has shown promise in improving insulin sensitivity in people at risk for type 2 diabetes. A recent study tested its…
2024-12-28

Clinical trials

A preliminary study of further attempt at the development, testing and application of an auxiliary equipment for electronic colonoscopy

A Preliminary Study on Improving Electronic Colonoscopy Background Colonoscopy is an important tool for screening colorectal cancer and routine health checks, becoming more common each year. In China, nurses typically…
2024-08-11

Clinical trials

Comparison ultrasound-guided adductor canal block and surgeon-performed block for pain management after total knee arthroplasty: a prospective randomized controlled study

Comparison of Ultrasound-Guided Adductor Canal Block and Surgeon-Performed Block for Pain Management after Total Knee Arthroplasty: A Prospective Randomized Controlled Study Objective: The study aimed to compare the effectiveness of…