Conditions: Leukemia, Myeloid, Acute
Interventions: Drug: DFP-10917; Drug: Venetoclax
Sponsors: Delta-Fly Pharma, Inc.
Not yet recruiting
Phase I/II Study of DFP-10917 in Combination With Venetoclax in Relapsed or Refractory Acute Myeloid Leukemia
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Clinical Research
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Intranasal Insulin Diminishes Postoperative Delirium and Elevated Osteocalcin and Brain Derived Neurotrophic Factor in Older Patients Undergoing Joint Replacement: A Randomized, Double-Blind, Placebo-Controlled Trial
Intranasal Insulin Reduces Postoperative Delirium in Older Patients Study Overview This study explored how intranasal insulin affects older patients after joint replacement surgery. It aimed to see if this treatment…
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Expanding Xpert MTB/RIF Ultra and LF-LAM testing for diagnosis of tuberculosis among HIV-positive adults admitted to hospitals in Tanzania and Mozambique: a randomized controlled trial (the EXULTANT trial)
EXULTANT Trial: Improving Tuberculosis Diagnosis in HIV-Positive Hospitalized Patients Overview The EXULTANT trial aims to evaluate a new screening strategy for diagnosing tuberculosis (TB) in hospitalized people living with HIV…
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Long-term safety, tolerability, and efficacy of eptinezumab in chronic cluster headache (CHRONICLE): an open-label safety trial
Background Chronic cluster headache is a rare but very painful condition that causes severe headaches without long breaks between attacks. It can be hard to treat because there are few…
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Cost-effectiveness of methenamine hippurate compared with antibiotic prophylaxis for the management of recurrent urinary tract infections in secondary care: a multicentre, open-label, randomised, non-inferiority trial
“`html Cost-effectiveness of Methenamine Hippurate vs. Antibiotic Prophylaxis for Recurrent Urinary Tract Infections Key Findings: Results from a multicentre trial showed that methenamine hippurate was on average less costly and…
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Photobiomodulation Therapy Outperforms Pharmacotherapy for Temporomandibular Disorders
Purpose of the Study This study looked at two different treatments to help people with temporomandibular disorders (TMDs), which cause pain and issues in the jaw. The two treatments compared…
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Bayesian Population Pharmacokinetic Modeling of Ondansetron for Neonatal Opioid Withdrawal Syndrome
Bayesian Population Pharmacokinetic Modeling of Ondansetron for Neonatal Opioid Withdrawal Syndrome Summary Ondansetron is a medication being tested for treating Neonatal Opioid Withdrawal Syndrome (NOWS) in newborns. This study analyzed…
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Enhancing Clinical Reasoning in Physical Therapy Education: The Role of AI-Based Linguistic Models
Understanding the Study Results This study looked at how using large AI-based language models (LLMs) could help physical therapy students improve their clinical reasoning skills. Here’s what we found: What…
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Outcomes in stage IIA versus stage IIB/III in the PALLAS trial [ABCSG-42/AFT-05/PrE0109/BIG-14-13])
Outcomes in Stage IIA vs. Stage IIB/III in the PALLAS Trial Background The PALLAS trial studied whether adding palbociclib to standard hormone therapy could lower the chances of breast cancer…
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Effective Screening Tools for Detecting Mental Disorders in High-Grade Glioma Patients: A Comparative Study
Understanding the Study Results This study looked at how well three different tools can help doctors find mental health issues in patients with high-grade glioma, a type of brain cancer.…
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The role of trimethoprim/sulfamethoxazole in preventing opportunistic infections in systemic lupus erythematosus patients receiving low-level immunosuppressive treatment: an open-label, randomized, controlled trial
The Role of Trimethoprim/Sulfamethoxazole in Preventing Infections in SLE Patients Study Overview This study focused on patients with systemic lupus erythematosus (SLE) who are at risk for infections while receiving…
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Effectiveness of couple education and counseling on uptake of cervical cancer screening among women in Southern Ethiopia: a cluster randomized trial
Effectiveness of Couple Education and Counseling on Cervical Cancer Screening Uptake Key Findings Cervical cancer is a significant global health issue, particularly in developing countries, due to low screening rates…
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Enhancing Colorectal Cancer Screening: Insights from Patients and GPs on Effective Communication Strategies
Understanding the Importance of Colorectal Cancer Screening Colorectal cancer (CRC) is a major cause of death around the world. Catching it early can save lives. In France, there is a…
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Improving Survival Rates in Pediatric T-ALL: Insights from the ALL-T11 Trial
Understanding the Clinical Trial Results for T-ALL T-cell acute lymphoblastic leukemia (T-ALL) is a type of blood cancer that affects children and young adults. This trial focused on patients under…
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Peri-Implant Diseases: Enhanced Antibacterial Photodynamic Therapy
Background The use of dental implants is growing, but many patients experience inflammation around these implants. This study explored how a special treatment called antibacterial dual-light photodynamic therapy (aPDT) can…
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Detection of Elder Abuse Through Emergency Care Technicians Screening Tool Revision for Home-Based Primary Care (DETECT-RPC): a cluster randomised controlled trial study protocol
Detection of Elder Abuse Through Emergency Care Technicians Screening Tool Revision for Home-Based Primary Care (DETECT-RPC) Study Overview The prevalence of elder mistreatment (EM) is concerning, especially among older adults…
