Conditions: Leukemia, Myeloid, Acute
Interventions: Drug: DFP-10917; Drug: Venetoclax
Sponsors: Delta-Fly Pharma, Inc.
Not yet recruiting
Phase I/II Study of DFP-10917 in Combination With Venetoclax in Relapsed or Refractory Acute Myeloid Leukemia
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Clinical Research
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Adherence to a low-fat dietary pattern reduces head and neck cancer risk: evidence from the PLCO trial
Adherence to a Low-Fat Diet Lowers Head and Neck Cancer Risk Study Overview The study focused on how a low-fat dietary pattern (LFD) affects the risk of head and neck…
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The effects of dietary protein on physical performance and body composition in middle age and older people having type II diabetes mellitus: a randomized pilot study
The Effects of Dietary Protein on Physical Performance in Older Adults with Type 2 Diabetes Study Overview This study looked at how increasing dietary protein can help older adults with…
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Lithium versus anticonvulsants and the risk of physical disorders – Results from a comprehensive long-term nation-wide population-based study emulating a target trial
“`html Study on Bipolar Disorder Medication and Physical Disorders Key Findings: Bipolar disorder is linked to higher rates of physical disorders. Study compared the effects of lithium, lamotrigine, and valproate…
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“Reducing Delirium in Schizophrenia: Benefits of Ultra-Brief Pulse Electroconvulsive Therapy”
Understanding the Study Results on Electroconvulsive Therapy (ECT) This study looked at how a new type of ECT, called ultra-brief pulse ECT, affects patients with schizophrenia, especially regarding the risk…
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Bridging the Gap: How Telephone Reporting of Patient-Reported Outcomes Improves Cancer Care Disparities
Understanding the PRO-TECT Trial Results The PRO-TECT trial looked at how patients report their symptoms during cancer treatment. It offered two ways for patients to share their health updates: through…
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Survival outcomes of population-wide colonoscopy screening: reanalysis of the NordICC data
Survival Outcomes of Colonoscopy Screening: Key Findings Background Colonoscopy is a common method used to screen for colorectal cancer, but strong evidence supporting its effectiveness is lacking. The NordICC trial,…
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Effect of endothelin-1 on the blood pressure response to acute hypoxia and hyperoxia in healthy young men
Effect of Endothelin-1 on Blood Pressure Response to Hypoxia and Hyperoxia in Young Men Physiological Reports, 2024 Sep;12(17):e70004 Endothelin-1 (ET-1) and its receptors have been linked to increased sensitivity to…
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Effects of Spirulina platensis supplementation on quality of life, severity of disease and serum total antioxidant capacity, malondialdehyde and zonulin in constipation-predominant irritable bowel syndrome: protocol for a randomised, double-blinded, placebo-controlled clinical trial from Iran
Introduction Irritable bowel syndrome (IBS) is a common condition affecting the gut and brain. Currently, there is no specific treatment for IBS. Factors like low-grade inflammation and oxidative stress may…
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“Introducing IMAGINE: A New Psychological Intervention for Adolescent Depression in Schools”
Understanding the IMAGINE Trial Results The IMAGINE trial aimed to test a new way to help teenagers dealing with depression in schools. This trial is important because it focuses on…
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Strength Training Benefits for Low Back Pain in Pregnant Women: In-Person vs. Remote Sessions
Understanding the Study This study looked at how one session of strength training, either in-person or online, affects low back pain and disability in pregnant women. It also checked how…
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Combined Treatment With Cognitive Behavioral Therapy for Insomnia and Acceptance and Commitment Therapy Enhances Objective and Subjective Reports of Sleep in Patients With Advanced Cancer
“`html Background People with advanced cancer often struggle with sleep problems. These issues can lead to bad moods, a lower quality of life, and even shorter survival times. Many patients…
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Lung Cancer Screening Before and After a Multifaceted Electronic Health Record Intervention: A Nonrandomized Controlled Trial
Lung Cancer Screening Intervention Trial Key Findings Lung cancer is the deadliest cancer in the US, but early detection through screening improves outcomes. A nonrandomized controlled trial assessed a multifaceted…
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The incidence and mortality of refeeding syndrome in older hospitalized patients, based on three different diagnostic criteria: A longitudinal study
Study on Refeeding Syndrome in Older Hospitalized Patients Background and Objectives Refeeding syndrome (RFS) lacks a global definition and diagnostic criteria. This study investigated the incidence of RFS and mortality…
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Cost-utility and cost-benefit analysis of a multi-component intervention (NEXpro) for neck-related symptoms in Swiss office workers
Cost-Utility and Cost-Benefit Analysis of NEXpro for Neck Pain in Office Workers Background Neck pain is a major health issue for office workers, affecting 42% to 68% of them. This…
