Public Health Update on Cognitive Decline Interventions
Background
Multidomain lifestyle changes may help slow down cognitive decline and prevent dementia. The U.S. POINTER trial is a significant study looking at how these lifestyle changes affect older adults at risk of cognitive issues.
Methods
We created four scores to measure how well participants engaged in the POINTER lifestyle interventions.
Results
- Composite Score One: Measures adherence to goals in physical activity, diet, and brain training. Scores range from 0 to 1.25, where 1 means the goal was met and 1.25 means it was exceeded.
- Composite Score Two: Uses Consistent Intervals to ensure fair measurement across all three domains, with scores ranging from 0 to 1.
- Composite Score Three: Applies a Proportional Approach to assess engagement based on the proportion of goals achieved.
- Composite Score Four: Utilizes Exploratory Factor Analysis to determine the best weighting for each domain’s scores.
We also looked at how to handle missing data in two ways: treating it as no adherence or using predictions to fill in gaps. We will analyze these scores to prepare for future studies.
Conclusion
We propose four composite scores to measure how well participants engage in the U.S. POINTER interventions. Future research will assess how sensitive these scores are to changes in cognitive function. This work will help improve other studies that track adherence in lifestyle interventions.
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