Quantitative Analysis of Essential Oil Mouthrinses on Plaque Microbiome
BMC Oral Health. 2024 May 18;24(1):578. doi: 10.1186/s12903-024-04365-9.
Background: The oral cavity’s microorganisms greatly impact oral health. This study introduces a new method to measure the effects of essential oil mouthrinses on dental plaque microbiome using DNA standards and metagenome sequencing.
Methods: In a randomized trial, three mouthrinses were compared against a control rinse for their impact on clinical parameters and oral microbiome in subjects with moderate gingivitis.
Results: The essential oil mouthrinses shifted the microbiome composition to a healthier state after four weeks of use. They also significantly reduced gingivitis and plaque compared to the control rinse after six weeks.
Conclusions: This study demonstrates that essential oil mouthrinses reset a gingivitis-like oral microbiome toward a healthy state through repeated use.
Trial Registration: Registered on ClinicalTrials.gov with the registration number NCT04921371.
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