Itinai.com an advertising light picture for medical analysis 5c395afe 218e 4906 a405 4791096c0e54 0
Itinai.com an advertising light picture for medical analysis 5c395afe 218e 4906 a405 4791096c0e54 0

Randomized controlled trial on the efficacy and safety of the combination therapy of topical 0.1% finasteride — 5% Minoxidil in male androgenetic alopecia

Study Overview

This study explored a new treatment for hair loss in men, specifically androgenetic alopecia (AGA). The focus was on combining two medications: topical finasteride (0.1%) and minoxidil (5%).

Current Treatments

Currently, the FDA has approved oral finasteride and topical minoxidil for treating AGA. This study looked at whether using both topical finasteride and minoxidil together could be more effective.

Study Details

The trial lasted 12 weeks and involved 40 men. They were divided into two groups: one group used both topical finasteride and minoxidil, while the other group only used minoxidil.

Results

After 12 weeks, both groups showed improvements in hair density and thickness. However, there were no significant differences between the two groups. Side effects included:

  • Reduced libido (in the minoxidil group)
  • Mild erectile dysfunction and chest pain (in the finasteride group)
  • Itching, shedding, and dandruff were common in both groups
  • One person had contact dermatitis from the treatment

Practical Healthcare Solutions

Measurable Outcomes

Clinics and patients should focus on:

  • Tracking changes in hair density
  • Monitoring hair thickness and health

Setting Clear Goals

Establish specific targets for improving hair growth and reducing side effects in patients undergoing treatment.

AI Tools for Clinical Needs

Select AI solutions that can help in:

  • Monitoring treatment progress
  • Analyzing patient data for better outcomes

Implementation Steps

Start with a pilot project to test the combination treatment. Use AI tools to track results and assess the real-world impact on patients.

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