Respiratory complications of propofol, sevoflurane, and dexmedetomidine anesthesia for fiberoptic bronchoscopy in children aged 1 month to 3 years: a randomized trial

Respiratory Complications in Children Under Anesthesia

Study Overview

This study looked at how different anesthesia methods affect respiratory issues in young children during fiberoptic bronchoscopy (FOB).

Objective

The goal was to compare the effects of propofol, sevoflurane, and dexmedetomidine on respiratory complications in children aged 1 month to 3 years.

Methods

A total of 120 children were randomly assigned to one of three anesthesia groups: sevoflurane inhalation, 1 mg/kg propofol, or 1 μg/kg dexmedetomidine. We monitored their heart rate, blood pressure, sedation levels, and any respiratory complications during and after the procedure.

Key Findings

  • Heart Rate and Blood Pressure: The dexmedetomidine group had a lower heart rate and higher blood pressure compared to the other groups.
  • Coughing: No coughing was reported in the propofol group, while the dexmedetomidine group had the most coughing incidents.
  • Laryngospasm: The propofol group had a lower incidence of laryngospasm (12.5%) compared to sevoflurane (30%) and dexmedetomidine (32.5%).

Conclusion

Both sevoflurane and propofol are safe and effective for anesthesia in children under 3 years old undergoing FOB. They provide better sedation and fewer respiratory complications compared to dexmedetomidine.

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