Role of ivermectin and colchicine in the treatment of COVID-19: a randomized controlled clinical trial

Role of Ivermectin and Colchicine in Treating COVID-19

Objective

This study aimed to evaluate how effective ivermectin and colchicine are as treatments for COVID-19.

Methodology

A clinical trial was conducted with three groups at Ain Shams University Hospitals. Participants with moderate COVID-19 were included, while those under 18, over 65, or with other health issues were excluded. Randomization was done using sealed envelopes, and patients were monitored for symptom improvement for over a month.

Results

A total of 120 patients participated in the study, with similar numbers in each treatment group. The main symptoms were fever and cough. The study found:

  • There was no significant difference in the duration of fever among the groups.
  • About 67.5% to 72.5% of patients recovered completely within 10 days, with no differences noted between treatment methods.
  • Inflammatory markers improved for all groups over time, but again, no significant differences were observed.

Conclusions

Ivermectin and colchicine did not provide any additional benefits over standard care for treating COVID-19.

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