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Saccharomyces boulardii combined with triple therapy alter the microbiota in the eradication of Helicobacter pylori infection

Saccharomyces boulardii combined with triple therapy alter the microbiota in the eradication of Helicobacter pylori infection

Study Title: Saccharomyces boulardii Combined with Triple Therapy for H. pylori Infection

Key Findings:

A clinical trial evaluated the effectiveness of combining Saccharomyces boulardii powder with triple therapy for eradicating H. pylori infection in patients with non-ulcer dyspepsia. The study included 144 patients and monitored microbial composition, eradication rates, symptom alleviation, and adverse reactions.

Results:

The combination of Saccharomyces boulardii with triple therapy showed promising results, with a higher eradication rate of 93.18% in the BRAC group compared to 75% in the SRAC group and 65.2% in the RAC group. Patients receiving Saccharomyces boulardii treatment also experienced a reduction in initial dyspepsia symptoms.

Practical Solutions and Value:

Combining Saccharomyces boulardii with triple therapy demonstrated notable efficacy in eradicating initial H. pylori infections among non-ulcer dyspepsia patients. This approach also showed advantages in alleviating symptoms, exhibited favorable tolerance, and maintained a high level of clinical safety.

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