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Short-term structured dietary and exercise interventions delay diabetes onset in prediabetic patients: a prospective quasi-experimental study

Study Overview

This study explored how structured dietary and exercise interventions can help delay diabetes in prediabetic patients. Prediabetes increases the risk of developing diabetes, and the researchers aimed to see if specific lifestyle changes could make a difference.

Participants

A total of 542 prediabetic patients participated in the study. They were selected based on common prediabetes criteria, including fasting blood glucose levels and hemoglobin A1c measurements.

Intervention Groups

Participants were randomly divided into four groups for 6 months:

  • Routine community intervention
  • Dietary intervention
  • Exercise intervention
  • Combined structured anti-inflammatory and antioxidant dietary and exercise interventions (SAIDEs)

Key Findings

After 6 months, all intervention groups showed:

  • Reduced body weight and blood pressure
  • Lower blood cholesterol and glucose levels
  • Improved β-cell function
  • Increased physical activity

Additionally, inflammatory markers in the blood improved significantly. Importantly, the prevalence of abnormal blood glucose markers decreased in all groups.

Long-term Impact

While the short-term interventions did not significantly reduce the overall incidence of diabetes over 8 years, they did delay its onset, especially in the group receiving SAIDEs.

Practical Healthcare Solutions

Measurable Outcomes

Clinics can set clear goals based on this study, such as:

  • Reducing patient body weight
  • Lowering blood glucose levels
  • Increasing physical activity

AI Tools for Clinical Needs

Healthcare providers can select AI solutions tailored to track and analyze patient progress in these areas.

Implementation Steps

Start with a pilot project to test these interventions, using AI tools to monitor results and real-world impacts.

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