“`html
Study Overview
A recent clinical trial investigated the effects of synbiotics (probiotics and inulin prebiotics) on patients with pancreatic ductal adenocarcinoma (PDAC) to improve their immune response and reduce postoperative complications. The study compared the combined use of synbiotics versus probiotics alone on 90 PDAC patients.
Key Findings
- The synbiotics group showed significant increase in CD8+ T cell proportion and IFN γ expression compared to the probiotics group, highlighting the enhanced immune response.
- Inflammatory cytokines decreased significantly in the synbiotics group compared to the placebo and probiotics-treated groups, indicating a reduction in inflammation.
- Both the synbiotics and probiotics groups experienced decreased postoperative complications such as anastomotic leakage, diarrhea, and abdominal distension, demonstrating the potential benefit of these interventions in improving patient outcomes.
Practical Implications
The findings suggest that the use of synbiotics and probiotics can provide practical solutions for improving immune response and reducing complications associated with surgery for PDAC patients. This approach has the potential to add value to the postoperative care and outcomes for individuals undergoing surgery for aggressive cancers like PDAC.
For the full clinical trial report, visit here.
“`
