Is the Phoenix Sign Linked to Blood Flow Changes? A Clinical Trial Overview Study Title: Evaluating motor function recovery after common fibular nerve block using lidocaine and papaverine. Published in: BMC Musculoskeletal Disorders, October 23, 2024. Background The common fibular nerve is the most frequently trapped nerve in the lower leg. Diagnosing this issue can…
Effect of Nutritional Supplements During Pregnancy Study Overview This study explores how high energy nutritional supplements can impact health markers related to heart and metabolism in underweight first-time pregnant women. Background Pregnancy increases nutritional needs, and inadequate maternal nutrition can lead to higher risks of heart and metabolic issues. This research is important as it…
The Effect of Low Molecular Weight Heparin Sodium in Treating Acute COPD with Pulmonary Heart Disease Overview Chronic obstructive pulmonary disease (COPD) affects about 13.7% of people over 40 in China, with nearly 100 million individuals suffering from it. This study focuses on how Low Molecular Weight Heparin Sodium can help treat acute exacerbations of…
Effects of Mobile Application-Based Cognitive Behavioral Therapy on Psychological Outcomes in Women Treated for Breast Cancer Study Overview This study focused on how a mobile app called Living Well can help improve mental health in women undergoing treatment for breast cancer. It was conducted in Germany and involved 70 female patients. Study Design Participants were…
The Effect of Coaching on Health Information Literacy in Patients with Chronic Kidney Disease Study Overview This study looked at how coaching affects health information literacy in patients with chronic kidney disease (CKD). CKD often goes unnoticed in early stages, leading to serious health issues. There is a need for better health education for these…
Effect of Ertugliflozin on Heart Function in Type 2 Diabetes and Pre-Heart Failure Study Overview This study investigates how well ertugliflozin, a type of medication for diabetes, works on heart function for people with type 2 diabetes and early signs of heart failure. Study Design In this randomized, double-blind trial lasting 24 weeks, we had…
Dynamic Sequential Cross-Sectional Scanning Improves Detection of Congenital Heart Disease Background Prenatal ultrasound is the best method for diagnosing congenital heart disease in fetuses. To address issues with physician skills and hospital access, we suggest using a new technique called dynamic sequential cross-sectional scanning (SCS) for sonographers with less than 5 years of experience. Methods…
Transcranial Direct Current Stimulation for Focal Refractory Epilepsy in Mitochondrial Disease (TRANSFORM) Study Overview This study investigates the effectiveness of Transcranial DC Stimulation (tDCS) for treating focal epilepsy in patients with mitochondrial disease. Focal epilepsy is common in these patients and can be hard to treat with medications, leading to serious conditions like refractory focal…
Ruxolitinib plus Steroids for Acute Graft Versus Host Disease A Multicenter, Randomized, Phase 3 Trial In patients newly diagnosed with high-risk acute graft-versus-host disease (aGVHD), clinical outcomes have historically been poor. This study evaluates combining ruxolitinib (RUX) with corticosteroids against using corticosteroids alone. Study Overview This phase 3 trial (ClinicalTrials.gov: NCT04061876) tested the safety and…
Anticoagulation Therapy Timing in Patients with Atrial Fibrillation after Subdural Haematoma Study Overview This study focuses on patients with subdural haematomas (SDHs) who need anticoagulant therapy for atrial fibrillation. Currently, there are no guidelines on when to safely resume anticoagulation after an SDH. Our research aims to explore if it is safe to start anticoagulation…
Study on Mindfulness to Reduce Caregiver Stress Overview Family caregivers of people with dementia often experience high levels of stress, which can harm their health. This study explores a simple mindfulness intervention that could help improve their mental well-being. We will test a single session combined with app support to see if it effectively reduces…
Development and Testing of a Mobile App for Managing Gestational Diabetes in Nepal Background Gestational diabetes mellitus (GDM) is becoming more common, especially in countries like Nepal. Managing GDM is essential to keep blood sugar levels in check and avoid complications. However, many people face challenges in managing their condition due to limited resources. Mobile…
Feasibility and Acceptability of a Digital Family Skills Program for Children with New Type 1 Diabetes Diagnosis Background Family dynamics significantly affect how children with Type 1 Diabetes (T1D) manage their condition. The period right after a T1D diagnosis can be very stressful for families. Providing support during this time can help improve health outcomes.…
The Link Between Medicine Sensitivity, Side Effects, and Personal Traits Study Overview This study investigates how a patient’s sensitivity to medicines (PSM) affects the side effects they report. Understanding this relationship is important because side effects can lead to personal and healthcare costs, such as not following treatment plans. We focused on patients with chronic…
Evaluating a Digital Tool for Breast Cancer Support: The ADAPT Study Purpose: This study examines how a digital tool aids self-management for individuals affected by breast cancer. It focuses on patient activation as the main goal, while also looking at health-related quality of life (HRQoL) and overall health status as secondary goals. Methods: Women with…
Pelvic Binder Radiography: A Safe Method for Assessing Pelvic Fractures Study Overview This clinical trial aimed to evaluate the safety and effectiveness of using a pelvic binder (PBR) to measure fracture stability in patients with lateral compression type 1 (LC1) pelvic fractures. Key Objectives To assess fracture displacement. To evaluate patient comfort during the procedure.…
Revefenacin Area Under the Curve Spirometry in Patients with Moderate to Very Severe COPD Study Overview This study focuses on the effectiveness of Revefenacin, a once-daily bronchodilator, in improving lung function in patients with chronic obstructive pulmonary disease (COPD). It highlights the importance of measuring lung function through various endpoints, including the area under the…
Reducing Rehospitalization in Cardiac Patients A Study on Cardiac Care Management Program in Germany Background: This study tested a new care management program that provides support to heart patients after they leave the hospital. We compared this program to standard care to see which was more effective. Methods: The study started in 2019/2020 and involved…
Study Overview of CHF6523 in COPD Management Background Chronic obstructive pulmonary disease (COPD) is a long-term inflammatory condition. Many patients still suffer from flare-ups, indicating a need for new anti-inflammatory treatments. Researchers have focused on a specific enzyme, phosphoinositide 3-kinase delta (PI3Kδ), to see if targeting it could help manage inflammation in COPD. What Was…
Study Overview This study investigates the impact of inaudible infrasound exposure on brain function and behavior, focusing on changes in brain connectivity. Key Findings 38 participants were exposed to inaudible infrasound for four weeks. Changes in brain connectivity were observed in various networks: Decreased connectivity in the right precuneus (part of the default mode network).…