Implementation of a rapid host-protein diagnostic test for distinguishing bacterial and viral infections in adults presenting to urgent care centers: a pragmatic cohort study

Implementation of a Rapid Diagnostic Test for Infections

Study Overview

This study evaluated a new blood test, MeMed BV® (MMBV), which can tell if an infection is bacterial or viral. The test was used in ten urgent care centers (UCCs) from April 2022 to March 2023. The main goal was to see how the test affected antibiotic use, and the secondary goal was to see how it helped doctors manage patients.

Study Methods

We conducted a pragmatic study with real-time reports from 144 physicians who ordered the MMBV test. They noted if they planned to prescribe antibiotics before the test and whether the test helped them after assessing the patient.

Key Results

  • 3920 MMBV tests were ordered for adults.
  • 19.3% of cases showed unnecessary antibiotic prescriptions, with doctors avoiding prescriptions in 63.1% of these cases.
  • 12.4% of cases had potentially missed bacterial infections, with 69.9% receiving antibiotic treatment.
  • Using MMBV was linked to fewer hospitalizations (7.8% vs. 30.3%).
  • Doctors reported that MMBV helped in managing patients in 86.0% of cases and avoided emergency referrals in 20.5% of cases.

Conclusion

Introducing MMBV in urgent care centers improved doctors’ decision-making, led to better antibiotic use, and enhanced patient management.

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