The effect of local anaesthetic agents on opioid use and recovery in patients undergoing open heart surgery: a randomized controlled study

The Effect of Local Anaesthetic Agents on Opioid Use and Recovery in Patients Undergoing Open Heart Surgery

BMC Cardiovasc Disord. 2025 Feb 1;25(1):72.

Background

After open heart surgery, patients often suffer from significant pain at the incision site and around chest tubes, which can slow recovery. This study aimed to see how local anaesthetic applied to these areas affects opioid use and recovery speed.

Methods

This study involved 60 patients, divided into two groups: 30 patients received local anaesthetic (LIDOFAST), and 30 patients received standard care only. Data were gathered using specific forms to assess patient characteristics and recovery.

Results

Patients who received the local anaesthetic experienced:

  • Delayed onset of postoperative pain
  • Reduced opioid use
  • Faster recovery compared to the control group

However, more chest tubes led to slower recovery across all groups. Increased opioid use also negatively impacted recovery in the control group.

Conclusions

Applying local anaesthetic around the sternotomy incision and chest tubes after surgery can decrease the need for opioids and enhance patient recovery.

Trial Registration

Current Controlled Trials NCT06642077

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