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Itinai.com biomedical laboratory close up still scene close u 2a5a1238 15e1 44d7 ad99 fe42b30c4e72 1

Tofacitinib is an effective treatment for moderate to severe ulcerative colitis, and intestinal ultrasound can discriminate response from non-response: a pragmatic prospective real-world study

Tofacitinib: Effective Treatment for Ulcerative Colitis

Highlights of the Study:

A pragmatic prospective study assessed tofacitinib’s efficacy for moderate to severe ulcerative colitis (UC).

Intestinal ultrasound (IUS) was evaluated as a tool to distinguish responders from non-responders in real-time.

Key Findings:

• 30 adult patients started tofacitinib; most had left-sided or extensive colitis and had previously failed biologic therapy.

• At week 8, 40% showed clinical response, 20% achieved remission, and 33.3% had endoscopic healing.

• IUS accurately discriminated treatment response from non-response at week 8.

Practical Solutions and Value:

Clinical trials are crucial for developing safe and effective treatments. Our AI-driven platform, DocSym, consolidates standards and research for clinicians.

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