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Transbronchial Needle Aspiration via Ultrathin Bronchoscope Improves Diagnostic Yield for Peripheral Lung Lesions: Randomized Sequencing Trial

Transbronchial Needle Aspiration via Ultrathin Bronchoscope Improves Diagnostic Yield for Peripheral Lung Lesions

Study Overview

This study investigates how combining ultrathin bronchoscopy with peripheral transbronchial needle aspiration (pTBNA) can enhance the diagnosis of peripheral pulmonary lesions (PPLs).

Key Findings

  • Improved Diagnostic Yield: The overall diagnostic yield was 66.3%, with pTBNA contributing an additional 11.9% of diagnoses.
  • Effective for Small Lesions: Lesions smaller than 20 mm benefited the most from this method.
  • High Accuracy: Of 70 malignant lesions, 71.4% were correctly diagnosed.
  • Complications: Pneumothorax occurred in 4% of cases, and moderate bleeding in 5%.

Practical Solutions and Value

The study shows that adding pTBNA to standard procedures can significantly improve diagnosis rates for lung lesions. This approach is particularly beneficial for smaller lesions and can lead to better patient outcomes.

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