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Summary of Recent Clinical Advances in Extraesophageal Reflux (EER) Management
Purpose of Review: The study discusses the increasing challenges faced by clinicians in dealing with symptoms and complications related to extraesophageal reflux (EER) and highlights the latest clinical advances in understanding its causes, testing, and treatments for upper and lower airway issues.
Recent Findings:
- Evidence suggests that laryngeal symptoms have multiple causes, including EER, oropharyngeal pathologies, allergic conditions, and cognitive-affective processes.
- A personalized approach using noninvasive strategies and prediction tools to identify patients at risk for EER is gaining traction.
- Management should include strategies targeting both reflux and other potential causes, especially for lower airway complications, which can impact lung function and transplant outcomes.
- Esophageal symptoms may not always be present, and routine testing for reflux may improve outcomes by guiding timely antireflux therapies.
- New diagnostic modalities leveraging impedance technology, such as mean nocturnal baseline impedance and postreflux swallow-induced peristaltic wave index, may provide valuable additional insights.
Summary: A standardized approach to diagnosing and managing EER should involve multidisciplinary care teams and consider various factors such as different patient phenotypes and gut-airway relationships. Timely antireflux therapies, tailored to individual candidates, could significantly improve outcomes for airway complications linked to EER.
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