Itinai.com close up of doctor hands doing procedure for patie b62daafd ae78 4416 b629 6e501ccde339 1
Itinai.com close up of doctor hands doing procedure for patie b62daafd ae78 4416 b629 6e501ccde339 1

Urine high-risk human papillomavirus testing as an alternative to routine cervical screening: A comparative diagnostic accuracy study of two urine collection devices using a randomised study design trial

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Study Summary

The study aimed to assess the effectiveness of using urine samples to detect high-grade cervical precancer (CIN2+) caused by human papillomavirus (HPV) using two different urine collection devices.

Key Findings

  • The sensitivity of HPV testing in urine samples collected with the FVU-collection device was 90.3%, higher than the standard pot which had a sensitivity of 73.4%.
  • Urine collected with the FVU-collection device showed promising sensitivity for CIN2+ detection.
  • Participants found urine self-sampling to be acceptable.

Practical Implications

  • Using the FVU-collection device for urine sampling can improve the detection of high-grade cervical precancer.
  • Urine-based testing using the FVU-collection device could be a potential alternative to routine cervical screening in the future.

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