Vonoprazan-amoxicillin dual therapy for Helicobacter pylori eradication in Chinese population: A prospective, multicenter, randomized, two-stage study

Vonoprazan-amoxicillin Dual Therapy for Helicobacter Pylori Eradication in Chinese Population

Study Overview

This study aimed to assess the effectiveness of Vonoprazan-amoxicillin dual therapy (VAT) for treating Helicobacter pylori (H. pylori) in the Chinese population.

Key Findings

The study found that VAT administered for 10 or 14 days achieved a higher eradication rate of H. pylori compared to standard bismuth quadruple therapy (BQT). The VAT groups also showed a more tolerable safety profile with fewer adverse events.

Practical Implications

The results suggest that using VAT for 10 or 14 days could offer a more effective and safer treatment option for H. pylori-infected patients in Fujian, China.

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