4-Aminopyridine treatment for nerve injury resulting from radical retro-pubic prostatectomy: a single-center double-blind, randomized, placebo-controlled study

4-Aminopyridine Treatment for Nerve Injury after Prostate Surgery

Background

Prostate cancer is a common and serious condition for men. Surgery to remove the prostate can lead to urinary incontinence and erectile dysfunction due to nerve injury. This study aims to evaluate the effectiveness of 4-aminopyridine (4AP) in improving these functions after surgery.

Methods

This study is a double-blinded, placebo-controlled trial involving patients who have undergone prostate surgery. They will receive either 4-aminopyridine or a placebo, and the study will assess how quickly their urinary and erectile functions return to baseline.

Discussion

This research is important as it could potentially reduce the negative effects of prostate surgery and identify patients who could benefit from further research into nerve injury.

Trial Registration

This trial is registered on ClinicalTrials.gov with the identifier NCT03701581.

Value

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