Study protocol for key interventions to improve the follow-up adherence postcervical precancerous lesion treatment in Ethiopia: a pragmatic randomised controlled trial

Study Overview

This study focuses on improving follow-up care for women treated for cervical precancerous lesions in Ethiopia. Follow-up care is essential to prevent cervical cancer, but many women do not return for necessary check-ups. Our goal is to find effective strategies to encourage these women to adhere to follow-up recommendations.

Key Interventions

We will test three main strategies to improve follow-up adherence:

  • Nurse-led telephone reminders
  • Home visits by health workers
  • Automated text message reminders through an app

In comparison, the standard care will only include verbal follow-up advice and a basic follow-up card.

Study Details

The study will start on November 1, 2024, and end on November 1, 2025. We will include 460 women aged 30-49 who are HIV-negative and those over 25 who are HIV-positive, all treated for suspicious cervical lesions. Participants will be divided into groups, with one group receiving the interventions and the other receiving standard care only.

Measuring Success

The main goal is to see how many women return for follow-up screenings after one year. We will analyze the results using various statistical methods to understand the effectiveness of our interventions.

Ethics and Communication

This study has received ethical approval from Addis Ababa University. We will share the results with participants and the wider community through workshops, conferences, and publications.

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