A pilot randomized clinical trial examining the effects of Qigong on inflammatory status and sleep quality in people with Parkinson’s disease

A Pilot Study on Qigong for Parkinson’s Disease

Background

Neuroinflammation is a key factor in the decline of neurons in people with Parkinson’s disease (PD). High levels of inflammatory markers, like IL-1β, IL-6, and TNF-α, are common in PD patients and relate to various non-motor symptoms. Qigong, a mind-body exercise, has been used to help those with PD. Previous research indicates a link between sleep quality and inflammation. This study looked at how Qigong affects inflammation and sleep quality in PD patients.

Methods

This was a randomized controlled trial with 17 participants. They underwent a 12-week program, with 8 doing Qigong and 9 doing a sham version. Participants filled out questionnaires about their non-motor symptoms, including sleep quality. Inflammatory markers were measured using a specialized assay.

Results

After 12 weeks, the Qigong group showed a trend of reduced IL-1β and IL-6 levels. There were also strong links between changes in IL-1β and improvements in sleep quality.

Conclusion

Inflammation plays a significant role in PD. This study suggests that Qigong may positively impact inflammation and sleep quality. More research is needed to confirm these findings.

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