Conditions: Hepatocellular Carcinoma
Interventions: Diagnostic Test: ctDNA monitoring; Diagnostic Test: Plasma proteomic analysis
Sponsors: Shanghai Zhongshan Hospital
Not yet recruiting
Biomarkers and Molecular Mechanism Study of Hepatocellular Carcinoma After Radical Resection and Conversion Therapy
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Clinical Research
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Prognostic value of plasma biomarkers for informing clinical trial design in mild-to-moderate Alzheimer’s disease
Background Recent studies show that blood tests can help diagnose and predict the progression of Alzheimer’s disease (AD), especially in its early stages. This research aimed to explore how these…
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Increasing coverage in cervical and colorectal cancer screening by leveraging attendance at breast cancer screening: A cluster-randomised, crossover trial
Increasing Cancer Screening Participation Study Overview: A clinical trial investigated the effectiveness of increasing cervical and colorectal cancer screening participation by leveraging attendance at breast cancer screenings. The trial was…
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Pelvic floor muscle training in women with urinary incontinence and pelvic organ prolapse: A protocol study
Pelvic Floor Muscle Training in Women with Urinary Incontinence and Pelvic Organ Prolapse: A Protocol Study Objective To assess the impact of pelvic floor muscle training (PFMT) on pelvic floor…
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Effectiveness of Self-Training With a Web-Based Digital Health Application Versus Physiotherapy in the Treatment of Disorders of the Patella: Randomized Controlled Trial
Background Knee injuries involving the patella are common. While exercise therapy is effective, challenges like appointment scheduling and limited sessions may hinder progress. Home-based exercise using digital health apps can…
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Enhancing Breast Cancer Treatment Knowledge in Surgeons: The Impact of Case-Based Learning and PDCA Integration
Understanding the Study Results The study focused on helping surgeons in county-level hospitals in China learn the most recent guidelines for breast cancer diagnosis and treatment. It looked at two…
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Enhancing Chronic Rotator Cuff Pain Management: Benefits of Graded Motor Imagery in Physiotherapy
Study Overview This study looked at how adding a method called Graded Motor Imagery (GMI) to regular physiotherapy can help people with chronic shoulder pain from rotator cuff issues. The…
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Efficacy and safety of methotrexate plus hydroxychloroquine combination therapy vs. methotrexate monotherapy in the treatment of rheumatoid arthritis: A randomized controlled clinical trial
Efficacy and Safety of Methotrexate Plus Hydroxychloroquine Combination Therapy vs. Methotrexate Monotherapy in the Treatment of Rheumatoid Arthritis: A Randomized Controlled Clinical Trial Key Findings: Combining methotrexate (MTX) with hydroxychloroquine…
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A clinical trial on pelvic floor sensory testing in women with and without stress urinary incontinence
Clinical Trial on Pelvic Floor Sensory Testing This study focuses on understanding how pelvic floor sensory training can help women with stress urinary incontinence (SUI). It compares the sensory abilities…
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Researchers at the University of Cambridge Propose AnchorAL: A Unique Machine Learning Method for Active Learning in Unbalanced Classification Tasks
Practical AI Solution: AnchorAL for Active Learning in Unbalanced Classification Tasks The development of language models has been greatly influenced by web-scale textual data. However, in real-world scenarios, the performance…
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Multifactorial balance rehabilitation in diabetic neuropathy elders: Randomized controlled trial
Overview of the Study This study looks at how a special balance rehabilitation program can help older adults with diabetic peripheral neuropathy (DPN). DPN is a common issue for people…
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Combined Methylprednisolone and Acoustic Resonance Therapy: Enhancing Recovery in Sudden Sensorineural Hearing Loss
Understanding the Trial Results What Worked? The combination of methylprednisolone sodium succinate (MPSS) and acoustic resonance therapy showed the best results for patients with sudden sensorineural hearing loss (SSNHL). Patients…
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Comparative efficacy and safety of nalbuphine and hydromorphone in painless colonoscopy techniques: a randomized controlled trial
Background Colonoscopy is important for finding problems in the colon, but it can be uncomfortable for patients. New techniques are being developed to make this process less painful. In these…
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Mobile App Use Alters Perceptions of Type 2 Diabetes: Key Findings for Healthcare Professionals
Understanding the Trial Results In this study, we looked at how a mobile app called forDiabetes can change the way people with type 2 diabetes see their condition. We had…
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Streamlined Genetic Education and Cascade Testing in Men from Hereditary Breast Ovarian Cancer Families: A Randomized Trial
Streamlined Genetic Education and Cascade Testing in Hereditary Cancer Families: Key Findings Introduction When a pathogenic BRCA1 or BRCA2 mutation is found in a family, it is important for family…
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Pentoxifylline ameliorates subclinical atherosclerosis progression in patients with type 2 diabetes and chronic kidney disease: a randomized pilot trial
Pentoxifylline Reduces Subclinical Atherosclerosis in Patients with Type 2 Diabetes and Chronic Kidney Disease Key Findings: Pentoxifylline (PTF) shows positive effects on the progression of subclinical atherosclerosis (SA) in patients…
