Biomarkers of inflammation in sweat after myocardial infarction

Inflammation Markers in Sweat After a Heart Attack

Study Overview: A heart attack called ST-elevation myocardial infarction (STEMI) causes a strong inflammatory response in the body. This study explores if sweat can be used to monitor this inflammation in a simple and non-invasive way.

Key Details:

  • We studied two groups of patients: 18 STEMI patients right after a heart procedure and 6 patients who had a different procedure without intervention.
  • We measured 92 inflammation markers in both sweat and blood using advanced testing methods.
  • Sweat markers remained stable over time, while blood showed changes, particularly a decrease in certain markers after several weeks.
  • One marker was found in higher levels in the sweat of STEMI patients compared to the other group.

Conclusion: While sweat is not as effective as blood for detecting inflammation right after a heart attack, using wearable sensors to analyze sweat could be valuable for long-term monitoring.

Trial Information: This study is registered at clinicaltrials.gov (NCT05843006).

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