Clinical trials

Effective Diabetes Management with Vitadio Managing diabetes effectively involves making lifestyle changes, taking medications, and educating patients continuously. However, many patients feel overwhelmed by the demands of self-management, which can lead to decreased motivation and poor health outcomes. Digital health apps like Vitadio are becoming essential tools to offer personalized support and improve diabetes management. […] ➡️➡️➡️

“`html Study Overview This study examined how a 7-day dietary supplement of grape seed extract (GSE) affects heart function and blood pressure in men with elevated and stage 1 hypertension. Key Findings GSE supplementation led to a decrease in resting diastolic blood pressure (DBP) and mean arterial pressure (MAP). No significant changes were observed in […] ➡️➡️➡️

Study Overview Recent research has shown that our moral decisions are influenced by emotions and personality traits. This study specifically looked at how a medication called lorazepam affects moral decision-making. Key Findings The study found that taking lorazepam did not significantly change people’s moral attitudes or judgments. This means that whether someone feels more anxious […] ➡️➡️➡️

Background Internet-based cognitive behavioral therapy for insomnia (iCBT-I) is a flexible treatment option. However, it takes up a lot of time and can include challenging parts like sleep restriction therapy. This raises questions about how effective it is compared to simpler options like sleep hygiene education. Objective This study aimed to compare the effectiveness of […] ➡️➡️➡️

Study Overview This study evaluated how a simple positioning aid device can improve neck CT scans for diagnosing thyroid cancer. The focus was on how this device affects image quality and diagnostic accuracy. Methods We conducted a randomized controlled trial with 180 patients suspected of having thyroid cancer. Patients were divided into two groups: Group […] ➡️➡️➡️

Study Overview This study looked at how injecting a patient’s own platelet-rich plasma (PRP) into the uterus affects women with thin endometrium who are trying to conceive using frozen embryos. Methods Seventy women with thin endometrium participated in this study. They were divided into two groups: one received a single PRP infusion, while the other […] ➡️➡️➡️

Background In patients with chronic obstructive pulmonary disease (COPD) using inhaled medications, guidelines suggest either increasing medication strength or switching to a different combination based on their symptoms and history of flare-ups. This study looked at the effects of increasing to a stronger combination versus switching to a different one on lung health and flare-up […] ➡️➡️➡️

Study Overview This study examined a new treatment for patients with paracentral keratoconus, a condition affecting the cornea of the eye. It compared two methods of accelerated corneal cross-linking (A-CXL): one that keeps the central part of the cornea intact (3 mm) and another that removes the entire outer layer of the cornea (epithelium). Key […] ➡️➡️➡️

Understanding the Day-Care Approach for Childhood Severe Pneumonia Severe pneumonia is a major cause of death in children under five in Bangladesh. A new Day-care management approach (DCA) was introduced in healthcare facilities to help manage this issue. This study aimed to understand the costs involved in using this new approach and how it varies […] ➡️➡️➡️

Background Cocaine and methamphetamine use disorders are serious health issues. Unfortunately, there are currently no FDA-approved treatments available for these conditions. The STIMULUS study is a clinical trial that aims to explore a new treatment option called repetitive transcranial magnetic stimulation (rTMS) for individuals with moderate to severe cocaine or methamphetamine use disorders. Study Overview […] ➡️➡️➡️

Background This study looked at how certain diabetes medications combined with a high-protein diet and moderate exercise can help people with obesity and newly diagnosed prediabetes or type 2 diabetes lose weight and possibly reverse their diabetes. Methods A total of 61 participants with obesity and recent diagnoses were split into two groups. One group […] ➡️➡️➡️

Background Interstitial cystitis (IC) is a long-lasting condition that causes pelvic pain and frequent urination. Current treatments often combine different therapies, but their success is still being studied. This research looked at a treatment plan that includes a special solution inserted into the bladder, along with other procedures, to see how well it works. Methods […] ➡️➡️➡️

Study Overview This study looked at how effective zirconia-reinforced glass ionomer (ZrGI) is in reducing pain and sensitivity in children with certain dental issues. It compared ZrGI to glass-hybrid glass ionomer (GhGI) in treating hypomineralized permanent first molars using the Atraumatic Restorative Treatment (ART) method. Study Details The research involved 88 children aged 7-10 with […] ➡️➡️➡️

Study Overview This study aimed to see how a new brief therapy led by general practitioners (GPs) could help reduce symptoms of post-traumatic stress disorder (PTSD) in patients who had been in intensive care. Study Design The research was conducted in 319 general practices across Germany. It involved 319 adults aged 18 to 85 who […] ➡️➡️➡️

Summary of Chuna Manual Therapy for TMJ Disorders The study investigates how effective and cost-effective Chuna manual therapy (CMT) is for treating temporomandibular joint disorders (TMD), specifically myofascial TMD. Study Overview A clinical trial was conducted from 2018 to 2019 with 80 patients suffering from TMJ pain for over three months. Patients were split into […] ➡️➡️➡️

Long-Term Safety and Efficacy of a New Dry Eye Treatment The ESSENCE-2 Open-Label Extension study focused on the long-term safety and effectiveness of a new eye drop treatment for dry eye disease (DED). This treatment is a water-free, non-preserved solution containing cyclosporine 0.1%, known as VEVYE. Study Overview This was a Phase 3 clinical trial […] ➡️➡️➡️

Understanding Enzalutamide and Prostate Cancer Treatment This research focuses on men with metastatic hormone-sensitive prostate cancer (mHSPC) and how treatment with enzalutamide combined with androgen deprivation therapy (ADT) affects their health outcomes, particularly through monitoring prostate-specific antigen (PSA) levels. Key Findings 1. Importance of PSA Levels: Lowering PSA levels after treatment is linked to better […] ➡️➡️➡️

Study Overview This study investigates the effects of MDMA-assisted therapy (MDMA-AT) on individuals with severe posttraumatic stress disorder (PTSD). It highlights the role of self-compassion in this therapy’s effectiveness. Key Findings MDMA-AT shows significant improvements in self-compassion among participants. Self-compassion is linked to reduced PTSD severity and depressive symptoms. Changes in self-compassion fully mediate the […] ➡️➡️➡️

“`html Study Overview This study compares different methods for removing epiretinal membranes (ERM) using advanced surgical technologies. PURPOSE The aim was to see how effective dye-assisted peeling is with a standard microscope compared to dye-free methods using two different advanced systems: microscope-integrated optical coherence tomography (Mi-OCT) and a three-dimensional heads-up display (3D-HUD). MATERIALS AND METHODS […] ➡️➡️➡️

Background Chronic obstructive pulmonary disease (COPD) can limit physical activity, making it hard for patients to move around. These patients often experience more cognitive issues than those without COPD. This study aimed to see how breathing training could help improve walking and thinking skills in COPD patients by changing their body position. Study Overview We […] ➡️➡️➡️