Clinical trials

Understanding the Trial Results This study looked at how to find and treat depression in people with serious cancer that is likely not curable. Here’s what they found: What Worked The method used to identify depression early was effective. They used health records to find patients who might be depressed. Patients who received a digital […] ➡️➡️➡️

Understanding the Trial Results The study looked at a treatment called bimekizumab (BKZ) for people with a type of arthritis known as axial spondyloarthritis (axSpA). It found that after two years, BKZ helped many patients feel better and see improvements in their symptoms. What Worked? Many patients saw their joint pain and inflammation decrease significantly. […] ➡️➡️➡️

Understanding the Trial Results The study looked at how frailty affects patients with heart failure and whether a medication called spironolactone helps improve frailty. Here’s what we found: What Worked? Improving frailty by more than 0.03 points on a specific scale is linked to better health outcomes. Patients who showed this improvement had a lower […] ➡️➡️➡️

Understanding the Study Results This study looked at how a new telehealth service, called the Epital Care Model (ECM), can help patients with chronic obstructive pulmonary disease (COPD). The main goals were to see if this service could improve mental well-being and reduce the need for health care visits, while also increasing social activities. What […] ➡️➡️➡️

Understanding the Study Results The study looked at how well two methods of measuring eye pressure agree: one using a special dye called fluorescein and the other without it. This is important for people in Ghana who may be tested for eye conditions like glaucoma. Key Findings The results showed that measuring eye pressure without […] ➡️➡️➡️

Understanding the Virtual Trier Social Stress Test (vcTSST) The Trier Social Stress Test (TSST) is a method used to create stress in a controlled way. This study looked at a new version called the virtual TSST (vcTSST), which can be done over Zoom. This method uses pre-recorded “jury” members to evaluate stress without needing multiple […] ➡️➡️➡️

Overview of the Research This study looked at how well targeted next-generation sequencing (tNGS) works for finding germs in newborns with serious breathing problems known as respiratory distress syndrome (RDS). The goal was to see if tNGS could help doctors find out what is causing the illness more quickly and accurately than traditional methods. What […] ➡️➡️➡️

Understanding the Study Results This study looked at a treatment called radiofrequency thermal coagulation (RF-TC) for patients suffering from trigeminal postherpetic neuralgia (TPHN), a type of severe pain that can occur after a shingles infection. The main goal was to see if this treatment could help reduce pain and inflammation in patients. What Worked? Effective […] ➡️➡️➡️

Understanding the Trial Results This study looked at a method to help doctors identify patients on continuous renal replacement therapy (CRRT) who might be at risk of needing more fluid support. The researchers tested a procedure called a 250-ml ultrafiltration challenge to see if it could effectively spot these patients. What Worked? The ultrafiltration challenge […] ➡️➡️➡️

Understanding the Study Results This study looked at how low doses of a medicine called rapamycin can help people with ME/CFS feel less tired and improve their symptoms. Here’s what we found: What Worked? Low-dose rapamycin (6 mg per week) was safe for patients. About 74% of patients who completed the study reported feeling less […] ➡️➡️➡️

Understanding the Trial Results This study looked at how a special AI tool, called a generative pretrained transformer (GPT), can help people running clinical trials. The focus was on a trial called Sleep SMART, which studies how sleep affects stroke recovery. The researchers wanted to see if this AI could quickly answer questions about the […] ➡️➡️➡️

Understanding the Trial Results This study looked at how using a cooling spray can help reduce pain during a mammogram, which is an important test for checking for breast cancer. What Worked? The cooling spray helped lower pain levels for women undergoing mammography, with an average pain score of 4.82 compared to 6.84 for those […] ➡️➡️➡️

Understanding the Study Results This study looked at a new imaging technique called Linked Color Imaging (LCI) to see if it could help doctors find more polyps during colonoscopies compared to the standard method, which uses white-light imaging (WLI). Polyps are growths in the colon that can sometimes lead to cancer if not found and […] ➡️➡️➡️

Understanding the Trial Results This study looked at how well a medication called esomeprazole helps people with functional dyspepsia (FD) during Ramadan fasting. Functional dyspepsia is a common stomach issue that causes discomfort, bloating, and nausea, especially when eating changes. The trial involved 245 patients who fasted during Ramadan. They were split into two groups: […] ➡️➡️➡️

Understanding the Montessori Preschool Study This study looked at how public Montessori preschool affects children by the end of kindergarten. It involved a large number of children from different schools across the country. What Worked? Children who attended Montessori preschool showed better skills in reading, memory, understanding others’ thoughts, and managing tasks. These improvements were […] ➡️➡️➡️

Trial Results Explained This study compared two treatments for knee osteoarthritis (KOA): High-Intensity Laser Therapy (HILT) and Ibuprofen Gel Phonophoresis (IGP). Both treatments helped reduce pain and improve movement, but HILT worked better than IGP. What Worked? High-Intensity Laser Therapy (HILT): This treatment used a strong laser for 15 minutes. It showed more improvement in […] ➡️➡️➡️

Understanding the Trial Results This study looked at how two treatments could help older adults with sarcopenic obesity, which means they have a lot of body fat and not enough muscle. The treatments tested were: TECAR Therapy: A method that uses energy to improve muscle and tissue health. HMB Supplement: A nutritional supplement that helps […] ➡️➡️➡️

Understanding the Study Results This study looked at how different sizes of orthokeratology (ortho-k) lenses affect vision quality in children who are nearsighted (myopic). The main goal was to see if using a larger or smaller lens made a difference in how well these children could see. Key Findings What Worked: Children who wore ortho-k […] ➡️➡️➡️

Understanding the Research on Knee Osteoarthritis This research compares two types of exercise programs for patients with knee osteoarthritis (OA) after receiving platelet-rich plasma (PRP) injections. Here’s what you need to know about the study results and their importance for patients and clinics. What Worked? Both supervised and home-based exercise programs helped reduce pain and […] ➡️➡️➡️

Understanding Postpartum Hemorrhage Diagnosis What is Postpartum Hemorrhage? Postpartum hemorrhage is when a woman loses a lot of blood after giving birth. It’s usually defined as losing 500 mL or more within the first 24 hours after vaginal delivery. Why is Timely Diagnosis Important? Knowing when and how postpartum hemorrhage occurs can help healthcare providers […] ➡️➡️➡️