Cognitive Processing Therapy for Posttraumatic Stress Disorder in Japan: A Randomized Clinical Trial

Cognitive Processing Therapy for PTSD in Japan

Overview

Cognitive Processing Therapy (CPT) is a proven treatment for posttraumatic stress disorder (PTSD). This study focuses on its effectiveness in Japan, where such evidence is limited.

Study Purpose

The goal was to determine if CPT effectively treats PTSD in outpatient settings in Japan.

Study Design

This randomized clinical trial lasted 16 weeks and included participants from a national psychiatric hospital in Tokyo. It compared CPT combined with standard treatment (CPT-TAU) to a waiting list with standard treatment (WL-TAU) from April 2016 to December 2022.

Participants

The study involved 60 adult patients with PTSD, with a majority being women (90%).

Intervention Details

Participants were divided into two groups:

  • CPT-TAU: 12 weekly individual CPT sessions (29 participants)
  • WL-TAU: Clinical monitoring and/or medication (31 participants)

Main Findings

The main measure of success was the Clinician-Administered PTSD Scale (CAPS-5) score after 17 weeks.

  • The CPT-TAU group had a significant reduction in CAPS-5 scores.
  • They also showed improvements in depression, suicidal thoughts, and overall disability.
  • There were no serious adverse events in the CPT-TAU group.

Conclusion

This trial indicates that CPT is an effective treatment for reducing PTSD symptoms in East Asian populations, providing strong evidence for its use in clinical practice.

Clinical Relevance

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