Effect of acupuncture on tic disorder: a randomized controlled clinical trial based on energy metabolomics and infrared thermography

Effect of Acupuncture on Tic Disorder: A Randomized Controlled Clinical Trial

BMC Complement Med Ther. 2024 Jun 20;24(1):240. doi: 10.1186/s12906-024-04534-x.

Background: Acupuncture is used to treat tic disorder, but there is a lack of clinical evidence supporting its efficacy. This study aims to investigate the potential mechanism of acupuncture in treating tic disorder by examining energy metabolism and infrared thermography in children with tic disorder.

Methods: The study will recruit 90 children, dividing them into a non-intervention group (30 healthy children) and an intervention group (60 children with tic disorder). The intervention group will be further divided into a treatment group and a control group. The treatment group will receive acupuncture and behavioral therapy, while the control group will receive sham acupuncture and behavioral therapy. Both groups will undergo 3 treatment sessions per week for 12 weeks. Outcome measures will include YGTSS, urinary and fecal metabolomics, and infrared thermography of the body surface. These measures will be collected at baseline and at the end of the 12-week period.

Discussion: The study aims to observe changes in tic severity, body surface thermography, and metabolomics after acupuncture treatment. The goal is to understand the possible mechanism of acupuncture in improving clinical symptoms and to develop clinical guidelines for diagnosing, treating, and assessing tic disorder.

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