Background
Coronary Artery Bypass Graft (CABG) surgery helps patients with Coronary Artery Disease (CAD) live longer. However, low levels of essential trace elements in the body can negatively affect these patients.
Objective
This clinical trial aimed to see how taking trace element supplements affects recovery after CABG surgery.
Methods
Two hundred patients who had CABG surgery were randomly given either a supplement called Addamel©, which contains important trace elements, or a saline solution for three days. We checked their blood for trace elements and a marker of inflammation called hs-CRP at different times after surgery. We also looked at how long they stayed in the hospital and ICU, their 30-day survival rate, and the occurrence of heart rhythm issues.
Results
Patients who received the Addamel supplement had higher levels of copper and manganese by day three. While inflammation levels increased for both groups on day one, they decreased in the supplement group by day two. The Addamel group had a lower death rate, although this difference wasn’t statistically significant. We found that lower zinc levels were linked to higher 30-day mortality, and higher pre-surgery CRP levels were associated with worse outcomes.
Conclusion
Trace element supplementation appears to help patients recovering from CABG surgery. Using Addamel for a short time after surgery may help maintain trace element levels and reduce inflammation.
Measurable Outcomes
We can set clear goals for how trace element supplementation affects recovery in patients undergoing elective cardiac surgery. This includes tracking changes in biochemical markers and overall health outcomes.
AI Tools
Select AI solutions that meet the specific needs of clinical practice to analyze the effects of trace element supplementation on patient outcomes.
Implementation
Start with a pilot project to test these solutions, monitor the results, and assess the real-world impact of trace element supplementation on patient recovery.
Contact Us
For more information on AI solutions in medical management, reach out to us:
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