Effects of a Circuit Training Program on Myokine Levels in Insulin-Resistant Women: A Randomised Controlled Trial

Effects of a Circuit Training Program on Myokine Levels in Insulin-Resistant Women

Study Overview

This study examined how circuit training affects myokine levels in women with insulin resistance. Myokines are substances released by muscles that help regulate glucose metabolism.

Methodology

We conducted a controlled trial with 42 women, dividing them into two groups:

  • Training Group: Participated in circuit training for 3 months, with three 33-minute sessions each week. This included both strength and endurance exercises.
  • Control Group: Maintained their usual activity without any changes.

We measured body composition and myokine levels (IL-6, IL-10, FGF21, and irisin) before and after the program.

Results

The training group showed a significant increase in serum IL-6 levels compared to the control group. However, there were no significant changes in IL-10, FGF21, and irisin levels between the groups.

Conclusion

The circuit training program effectively increased IL-6 levels in women with insulin resistance, highlighting its potential benefits for managing this condition.

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