Efficacy of delivery of care with Tele-continuous EEG in critically ill patients: a multicenter randomized controlled trial (Tele-cRCT study) study

Efficacy of Tele-EEG in Critically Ill Patients

Study Overview

This study looked at the effectiveness of Tele-continuous EEG (Tele-cEEG) compared to Tele-routine EEG (Tele-rEEG) for critically ill patients. The main focus was on seizure detection, mortality rates, and functional outcomes.

Study Details

The research took place over three years in eight hospitals in Thailand. It involved critically ill patients aged 15 and older who were at risk for seizures. Patients received either:

Tele-cEEG: monitored for 24-72 hours
Tele-rEEG: monitored for 30 minutes

The study tracked the outcomes at various times, including hospital discharge and up to one year later.

Results Summary

A total of 254 patients participated: 128 received Tele-cEEG and 126 received Tele-rEEG. The findings showed:

Seizures were detected slightly more with Tele-cEEG (21.88%) compared to Tele-rEEG (14.29%), but not significantly.
No significant difference in mortality rates was found between the two groups.
Functional outcomes were similar for both groups.

Conclusions

Both Tele-cEEG and Tele-rEEG were feasible options. However, Tele-cEEG needs more EEG specialists and resources. While Tele-cEEG might help detect seizures better, the study was not strong enough to show a clear benefit in reducing death rates or improving recovery.

For settings with limited resources, Tele-rEEG is a good starting point for screening patients at risk for seizures. If Tele-cEEG is available, it is the preferred method.

Clinical Trial Registration

This trial is registered with the Thai Clinical Trials Registry (TTCTR20181022002).

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