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Exploring the therapeutic impact of Salvia officinalis on lipid and oxidative stress markers in patients with polycystic ovary syndrome — a randomized placebo-controlled clinical trial

Study Overview

This study looked at the effects of Salvia officinalis (also known as sage) on women with Polycystic Ovary Syndrome (PCOS). It aimed to see how this herb could help with metabolism and reduce oxidative stress in patients.

Study Details

The research was conducted in gynecology clinics in Iran. A total of 70 married women aged 15-40 with newly diagnosed PCOS participated. They were divided into two groups: one received 330 mg of Salvia officinalis extract daily, while the other group received a placebo (a non-active substance) for eight weeks.

Key Findings

After the eight weeks, the results showed:

  • Lower triglyceride levels (a type of fat in the blood)
  • Reduced levels of malondialdehyde, a marker of oxidative stress
  • Significant changes in overall lipid profile and antioxidant capacity in the group taking the extract

Conclusion

The study concluded that Salvia officinalis extract can effectively lower triglyceride levels and oxidative stress in women with PCOS. This suggests it could be a helpful natural treatment for managing metabolic issues related to this condition.

Next Steps for Clinics and Patients

Based on these findings, clinics can:

  • Set clear goals to measure improvements in lipid profiles and oxidative stress markers in patients.
  • Consider implementing Salvia officinalis as a complementary treatment for PCOS.
  • Explore AI tools that can help track patient progress and outcomes related to this treatment.

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