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Fluorescence-Guided Laparoscopy for Staging of Gastric Cancer
Practical Solutions and Value
- Hypericin, a fluorescent compound from plants, was tested to improve visualization of peritoneal metastasis (PM) in gastric cancer (GC) through laparoscopy.
- Study aimed to assess safety and feasibility of oral hypericin and the effectiveness of fluorescence-guided laparoscopy (FGL) for staging GC.
- Patients received Laif® 900, a hypericin-containing product, before undergoing white and ultraviolet light laparoscopy.
- Findings showed that FGL was feasible but did not significantly improve PM detection in this study.
- Authors suggested ensuring sufficient hypericin levels in target tissue before reconsidering FGL with hypericin.
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