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Itinai.com biomedical laboratory close up still scene close u e4996bf4 1113 41b3 8fdd 0d1e6c918068 0

Maintenance therapy with anlotinib after induction therapy with platinum-based chemotherapy for advanced non-small-cell lung cancer: A pooled analysis of 2 single-arm trials

Maintenance Therapy with Anlotinib for Advanced Non-Small-Cell Lung Cancer

Key Findings

Maintenance therapy with anlotinib after platinum-based chemotherapy showed a median progression-free survival of 5.95 months and a median overall survival of 18.60 months in patients with advanced non-small cell lung cancer.

Results

Out of 23 patients, 19 had stable disease, 1 had a partial response, and 3 had progressive disease. The objective response rate was 4.35%, and the disease control rate was 86.96%. The incidence of adverse events of grade ≥ 3 was 21.7%.

Conclusion

Anlotinib offers a new option for maintenance treatment in patients with locally advanced or metastatic NSCLC after standard first-line platinum-based chemotherapy.

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