Molecular Landscape and Therapeutic Strategies against Colorectal Cancer

Practical Solutions and Value

Colorectal cancer (CRC) is the second leading cause of cancer deaths worldwide.
Incidence of young-onset CRC (diagnosis before age 50) is increasing.
Improved outcomes for CRC patients due to comprehensive molecular characterization of tumors and novel therapeutic strategies.
Advances in genomic and transcriptomic analyses have identified distinct tumor subtypes with unique biological characteristics and therapeutic vulnerabilities.
Targeted therapies and immunotherapy are now incorporated into CRC treatment.
Discussion of the molecular landscape and key oncogenes/tumor suppressors contributing to CRC tumorigenesis, metastasis, and therapeutic resistance.
Personalized therapeutic strategies for subsets of CRC patients.
Overview of evolving novel treatments being evaluated in clinical trials.

Full research Molecular Landscape and Therapeutic Strategies against Colorectal Cancer: https://pubmed.ncbi.nlm.nih.gov/38672633/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=1B1L42DK3a-JWCV4P_PtHHBmWjwBLFNcDXsYJkbqjQD0Ca7UQh&fc=None&ff=20240427133354&v=2.18.0.post9+e462414

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Sonolysis during carotid endarterectomy: randomised controlled trial

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Comparing Platelet-Rich Plasma and Nerve Ablation for Knee Osteoarthritis Pain Relief

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A Tailored Postpartum eHealth Physical Activity Intervention for Individuals at High Risk of Postpartum Depression-the POstpartum Wellness Study (POW): Protocol and Data Overview for a Randomized Controlled Trial

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Impact of Probiotic Supplementation and High-Intensity Interval Training on Primary Dysmenorrhea: A Double-Blind, Randomized Controlled Trial Investigating Inflammation and Hormonal Modulation

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Clinical trials

«There’s a lot of unknowns»: a thematic analysis of the experiences of young adults with cancer who died during a psychosocial intervention trial

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Potential Harms of Feedback After Web-Based Depression Screening: Secondary Analysis of Negative Effects in the Randomized Controlled DISCOVER Trial

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The effect of Chinese herbal medicine on male factor infertility: study protocol for a randomized controlled trial

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The efficacy of narrowband ultraviolet B phototherapy combination with tofacitinib in the treatment of vitiligo: a randomized controlled trial

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Cost-Effectiveness of HIV Screening in Emergency Departments: Results From the Pragmatic Randomized HIV Testing Using Enhanced Screening Techniques in Emergency Departments Trial

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Innovation

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Molecular Landscape and Therapeutic Strategies against Colorectal Cancer

Molecular Landscape and Therapeutic Strategies against Colorectal Cancer

Practical Solutions and Value

Full research Molecular Landscape and Therapeutic Strategies against Colorectal Cancer: https://pubmed.ncbi.nlm.nih.gov/38672633/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=1B1L42DK3a-JWCV4P_PtHHBmWjwBLFNcDXsYJkbqjQD0Ca7UQh&fc=None&ff=20240427133354&v=2.18.0.post9+e462414

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Clinical Research

Sonolysis during carotid endarterectomy: randomised controlled trial

Comparing Platelet-Rich Plasma and Nerve Ablation for Knee Osteoarthritis Pain Relief

Impact of Probiotic Supplementation and High-Intensity Interval Training on Primary Dysmenorrhea: A Double-Blind, Randomized Controlled Trial Investigating Inflammation and Hormonal Modulation

«There’s a lot of unknowns»: a thematic analysis of the experiences of young adults with cancer who died during a psychosocial intervention trial

Potential Harms of Feedback After Web-Based Depression Screening: Secondary Analysis of Negative Effects in the Randomized Controlled DISCOVER Trial

Ear pain analyzer: Is it infection, wax, or pressure?

The efficacy of narrowband ultraviolet B phototherapy combination with tofacitinib in the treatment of vitiligo: a randomized controlled trial

Cost-Effectiveness of HIV Screening in Emergency Departments: Results From the Pragmatic Randomized HIV Testing Using Enhanced Screening Techniques in Emergency Departments Trial

This AI Paper from Peking University and ByteDance Introduces VAR: Surpassing Diffusion Models in Speed and Efficiency

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