Smart Healthcare

Mycophenolate Mofetil and New-Onset Systemic Lupus Erythematosus: A Randomized Clinical Trial

Mycophenolate Mofetil and New-Onset Systemic Lupus Erythematosus: A Randomized Clinical Trial

Key Findings

The study found that early use of mycophenolate mofetil (MMF) alongside prednisone and hydroxychloroquine sulfate reduced the risk of severe flare and incidence of lupus nephritis in patients with new-onset systemic lupus erythematosus (SLE) and a high titer of anti-double-stranded DNA (dsDNA) antibody without major organ involvement.

Study Details

The trial enrolled 130 treatment-naive patients aged 18 to 65 years in China and compared the efficacy and safety of MMF plus prednisone and hydroxychloroquine sulfate with prednisone and hydroxychloroquine sulfate alone over 96 weeks.

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Value

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