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Itinai.com close up of doctor hands doing procedure for patie b62daafd ae78 4416 b629 6e501ccde339 0

Phage therapy analysis of effectiveness in comorbid patients with wounds and surgical infections of various etiology based on the results of a comparative clinical study

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Background

Infections from wounds can be tough to treat, especially with bacteria becoming resistant to common antibiotics. This highlights the need for new treatment methods that are proven effective through reliable testing.

Objective

This study aimed to evaluate how well phage therapy works compared to traditional treatments for patients with various types of surgical infections.

Methods

We conducted a clinical trial with 70 adult patients suffering from serious skin, soft tissue, and bone infections. The study took place at a specialized medical center. We monitored various health indicators, including swelling, pain, and wound healing, over eight days.

Results

All patients had serious wounds that needed surgical cleaning. We divided them into three groups:

  • Group 1: Received phage therapy.
  • Group 2: Received phage therapy plus a special vacuum treatment.
  • Group 3: Received traditional antibiotic treatments.

Results showed that Group 2 had the best outcomes, with signs of healing appearing within four days. All groups showed good tolerance to the treatments, and no serious side effects were reported. Importantly, no additional surgeries were needed.

Conclusion

The study suggests that phage therapy is a promising option for treating difficult infections, especially when antibiotics fail. Combining different treatment methods, particularly using phages, can enhance healing. Future healthcare practices should focus on using phage therapy and finding effective ways to deliver these treatments directly to infection sites.

Next Steps

Clinics should set clear goals for using phage therapy based on these findings. Starting with pilot projects can help track effectiveness and improve patient outcomes.

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