Radiofrequency ablation via catheter and transpapillary access in patients with cholangiocarcinoma (ACTICCA-2 trial) — a multicenter, randomized, controlled, open-label investigator-initiated trial

Radiofrequency Ablation for Bile Duct Cancer (ACTICCA-2 Trial)

Key Findings and Practical Solutions

The ACTICCA-2 trial assessed the impact of adding radiofrequency ablation (RFA) to biliary stenting in patients with unresectable bile duct cancer undergoing palliative systemic therapy.

Patients were randomized to receive either RFA plus bile duct stenting or bile duct stenting alone, with both groups receiving palliative systemic treatment.

The primary endpoint was the time to first biliary event, with secondary endpoints including overall survival, safety, quality of life, clinical event rate, and hospital stays.

The study aims to evaluate the efficacy and safety of adding RFA to bile duct stenting in patients with bile duct cancer receiving palliative systemic treatment.

Value and Implications

Clinical trials like ACTICCA-2 are crucial for assessing new treatment approaches and improving patient outcomes.

By integrating AI-driven platforms and mobile apps into healthcare settings, clinics can streamline operations, monitor treatments, and improve patient care, ultimately enhancing workflows and reducing paper routines.

These advancements can help extend the benefits of clinical trials into everyday medical practice, ultimately improving patient outcomes and expanding digital healthcare services.

Learn more about how AI can enhance workflows and improve patient outcomes at aidevmd.com.

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