Conditions: Solid Tumor, Adult; BRCA1 Mutation; BRCA2 Mutation; Ovarian Cancer; Breast Cancer; Prostate Cancer
Interventions: Drug: ACE-86225106 tablet
Sponsors: Acerand Therapeutics (Shanghai) Limited
Recruiting
Study of ACE-86225106 to Treat Patients With Advanced Solid Tumors
AI-Powered Health Tools
Interactive AI Tools to Help You Understand Your Health
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AI checker for signs of blood cancer: Are your symptoms serious?
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Check if your sore throat is strep or viral with AI symptom logic
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Evaluate immune weakness: AI assesses frequent infections and fatigue patterns
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Is your sore throat viral or bacterial? Enter symptoms for instant AI check
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Persistent phlegm or mucus? AI analyzes color and frequency for insight
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Dribbling after urination? Use AI to check for incomplete bladder emptying
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Interpret your tumor marker test: Enter CA-125, PSA, or CEA for analysis
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Back pain checker: Use AI to assess severity and possible causes
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Do your symptoms match fibromyalgia? AI analyzes chronic pain patterns
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Palpitations? Use AI to assess if it’s anxiety or arrhythmia
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Sjögren’s syndrome checker: Dry eyes and mouth? AI analyzes autoimmune risk
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Check your snoring risk: AI bot evaluates if it’s harmless or sleep apnea
Solutions for Smart Healthcare
Clinical Research
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Vonoprazan-amoxicillin dual therapy for Helicobacter pylori eradication in Chinese population: A prospective, multicenter, randomized, two-stage study
Vonoprazan-amoxicillin Dual Therapy for Helicobacter Pylori Eradication in Chinese Population Study Overview This study aimed to assess the effectiveness of Vonoprazan-amoxicillin dual therapy (VAT) for treating Helicobacter pylori (H. pylori)…
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Pegylated Liposomal Doxorubicin Combined with Cytarabine and Granulocyte Colony-Stimulating Factor for Treating Newly Diagnosed Older and Unfit Acute Myeloid Leukemia Patients: A Prospective, Single-Center, Single-arm, Phase II Study
Background There are few effective treatments for older patients with acute myeloid leukemia (AML). A study was done to test a new treatment combining pegylated liposomal doxorubicin (PLD), low-dose cytarabine…
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Study protocol of an early randomized intervention trial assessing the metabolic effects of two levels of exercise intensity in children undergoing cancer treatment: the APACIS study
Background Insulin sensitivity is important for preventing metabolic diseases, especially in adults who survived childhood cancer. The APACIS study aims to explore how two different exercise programs can improve health…
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Enhancing COPD Care: How Discussing Sexuality Boosts Physical Activity and Quality of Life
Understanding the COSY Study Results The COSY study looked at how talking about sexuality can help people with chronic obstructive pulmonary disease (COPD) feel better and be more active. This…
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Place of telemedicine in the organization of emergency care: feasibility and benefits
Feasibility and Benefits of Telemedicine in Emergency Care Introduction Telemedicine involves remote patient care using new information and communication technologies. This study evaluates the remote management of patients in emergency…
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The effects of TECAR therapy on pain, range of motion, strength and subscale of HAGOS questionnaire in athletes with chronic adductor related groin pain: a randomized controlled trial
The Impact of TECAR Therapy on Athletes with Groin Pain Study Overview This study investigates how TECAR therapy affects pain, movement, strength, and the HAGOS questionnaire in athletes suffering from…
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Flavonoid-Enriched Orange Juice: A Dietary Strategy to Improve Metabolic Health in Obese Patients
Understanding the Trial Results This study looked at how drinking a special orange juice with added nutrients called flavonoids can help people who are obese. The trial involved 44 participants…
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Transverse versus longitudinal skin incision in first extensor tendon release for radial styloid tenosynovitis: a randomized controlled trial
Transverse vs. Longitudinal Skin Incision in Surgery for De Quervain’s Tenosynovitis Study Overview De Quervain’s tenosynovitis causes pain and swelling near the wrist. When non-surgical treatments fail, surgery is often…
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Educational intervention on perceived stress among adults with type 2 diabetes and metabolic syndrome: a non-randomized clinical trial
Educational Intervention on Perceived Stress in Adults with Type 2 Diabetes and Metabolic Syndrome Key Findings from the Clinical Trial During the six-month non-randomized clinical trial, a nurse-led educational health-promoting…
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Innovative Photodynamic Therapy Prolongs Survival in Peripheral Lung Cancer
Understanding the Trial Results of Photodynamic Therapy for Peripheral Lung Cancer What is Photodynamic Therapy (PDT)? Photodynamic Therapy (PDT) is a treatment that uses a special light-sensitive drug and a…
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Efficacy and Safety of Fexuprazan Versus Esomeprazole for Gastroesophageal Reflux Disease-Related Chronic Cough: A Randomized, Double-Blind, Active-Controlled Exploratory Trial
Study Overview This study looked at a new type of medication called potassium-competitive acid blockers (P-CABs), specifically fexuprazan, to see how well it works for people with chronic cough related…
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Implementation of Site-Specific Hepatitis C Virus Treatment Workflows for Vulnerable, High-Risk Populations: A Prospective Single-Arm Trial
Hepatitis C Treatment for Vulnerable Populations Introduction Hepatitis C virus (HCV) can be effectively treated with new medications, but many vulnerable groups struggle to access this treatment. Objective This study…
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Outcomes Following a Mental Health Care Intervention for Children in the Emergency Department: A Nonrandomized Clinical Trial
“`html Importance of Emergency Departments for Children’s Mental Health The emergency department (ED) plays a crucial role in helping children facing mental and behavioral health crises. It acts as a…
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Additional copies of 1q negatively impact the outcome of multiple myeloma patients and induce transcriptomic deregulation in malignant plasma cells
Impact of Additional Copies of Chromosome 1 Long Arm in Multiple Myeloma Patients Key Findings: Patients with amplification (Amp1q, ≥4 copies of 1q) or gain (Gain1q, 3 copies of 1q)…
