Conditions: Solid Tumor, Adult; BRCA1 Mutation; BRCA2 Mutation; Ovarian Cancer; Breast Cancer; Prostate Cancer
Interventions: Drug: ACE-86225106 tablet
Sponsors: Acerand Therapeutics (Shanghai) Limited
Recruiting
Study of ACE-86225106 to Treat Patients With Advanced Solid Tumors
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Clinical Research
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After the program ends: HIV testing behavior among men who have sex when men after the conclusion of a program providing regular home delivery of HIV self-testing kits
HIV Testing and Self-Testing Programs HIV testing is crucial for preventing the spread of the virus, especially among at-risk groups like gay and bisexual men. Self-testing for HIV (HIVST) can…
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Effective Peer Support Reduces Postpartum Depression and Anxiety in New Mothers
Study Overview The study looked at how well a program called “Mom Supports Mom” helps women dealing with mental health issues after having a baby. These issues, if not treated,…
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Phase IB part of LOC-R01, a LOC network non-comparative randomized phase IB/II study testing R-MPV in combination with escalating doses of lenalidomide or ibrutinib for newly diagnosed primary central nervous system lymphoma (PCNSL) patients
Phase IB Study on Induction Therapies for Primary Central Nervous System Lymphoma Overview A study was conducted to improve treatment for primary central nervous system lymphoma (PCNSL) patients. The trial…
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Urine high-risk human papillomavirus testing as an alternative to routine cervical screening: A comparative diagnostic accuracy study of two urine collection devices using a randomised study design trial
“`html Study Summary The study aimed to assess the effectiveness of using urine samples to detect high-grade cervical precancer (CIN2+) caused by human papillomavirus (HPV) using two different urine collection…
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Effectiveness of flaxseed consumption and fasting mimicking diet on anthropometric measures, biochemical parameters, and hepatic features in patients with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): a randomized controlled clinical trial
Effectiveness of Flaxseed and Fasting Mimicking Diet in Managing MASLD Study Overview This study explored how combining flaxseed and a fasting mimicking diet (FMD) affects patients with Metabolic Dysfunction-Associated Steatotic…
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Efficacy and safety of eliapixant in endometriosis-associated pelvic pain: the randomized, placebo-controlled phase 2b SCHUMANN study
Efficacy and Safety of Eliapixant in Endometriosis-Associated Pelvic Pain: The SCHUMANN Study Published in BMC Women’s Health, June 19, 2024 Background: The SCHUMANN study assessed the effectiveness and safety of…
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Regression and growth rates in androgen deprivation therapy for advanced castration-sensitive prostate cancer
Research Overview This study focuses on comparing cancer regression (d) and growth (g) rates in patients with advanced castration-sensitive prostate cancer (CSPC) undergoing androgen deprivation therapy (ADT). Purpose The goal…
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The Effect of Information on the Time Course of Pain During an Episode of Acute Experimentally Induced Low Back Pain-A Randomised Experiment
Study Overview This study looked at how different types of information affect pain levels in people experiencing low back pain (LBP) after a specific exercise. Study Details Fifty healthy individuals…
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High definition transcranial direct current stimulation as an intervention for cognitive deficits in Alzheimer’s dementia: A randomized controlled trial
High Definition Transcranial Direct Current Stimulation for Alzheimer’s Dementia Overview This study explored a new, non-invasive technique to help with cognitive issues in Alzheimer’s dementia (AD). It aimed to see…
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Digital Health Interventions: Boosting Mental Well-Being in Older Adults through Lifestyle Changes
Understanding the MovingTogether Trial Results The MovingTogether trial looked at how a digital program could help improve mental health for older adults. Here’s what we found: What Worked? The MovingTogether…
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Innovative Home-Based Self-Swabs and Patient-Reported Outcomes for Tracking Influenza-Like Illness in Seniors
Understanding the DANFLU-2 HomeSwab PRO Study The DANFLU-2 HomeSwab PRO study looked at how well self-swabs and digital questionnaires work for tracking flu-like illnesses in older adults. Here’s what we…
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Reproductive Outcomes in Young Women with Early-Stage Cervical Cancer Greater than 2 cm Undergoing Fertility-Sparing Treatment: A Systematic Review
“`html Reproductive Outcomes in Young Women with Early-Stage Cervical Cancer Greater than 2 cm Undergoing Fertility-Sparing Treatment: A Systematic Review Summary Cervical cancer is a significant concern for young women.…
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Facing depression: evaluating the efficacy of the EmpkinS-EKSpression reappraisal training augmented with facial expressions — protocol of a randomized controlled trial
Facing Depression: A New Approach to Treatment Study Overview: This clinical trial aims to improve depression treatment by evaluating a new training method that combines cognitive restructuring with facial expression…
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Collateral benefits of ivermectin mass drug administration designed for malaria against headlice in Mopeia, Mozambique: a cluster randomised controlled trial
Background Head lice are common worldwide, especially in rural areas with lower incomes. They cause severe itching and can lead to infections that may have serious health effects. Ivermectin is…
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Evaluating Patient-Reported Outcomes in Treating Skeletal Class III Malocclusion in Adolescents
Understanding the Trial Results This study looked at two different treatments for young patients with a specific dental issue called skeletal class III malocclusion, which means their upper jaw is…
