Conditions: Solid Tumor, Adult; BRCA1 Mutation; BRCA2 Mutation; Ovarian Cancer; Breast Cancer; Prostate Cancer
Interventions: Drug: ACE-86225106 tablet
Sponsors: Acerand Therapeutics (Shanghai) Limited
Recruiting
Study of ACE-86225106 to Treat Patients With Advanced Solid Tumors
AI-Powered Health Tools
Interactive AI Tools to Help You Understand Your Health
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AI checker for signs of blood cancer: Are your symptoms serious?
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Do your symptoms match early leukemia signs? Use AI for instant check
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Blood in stool or urine? Use AI bot to assess if it’s a cancer warning sign
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Check your PSA level: Enter value for instant prostate health analysis
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Bladder control problems? Use the AI tool to evaluate incontinence risk
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Check your resting heart rate: Find out if it’s normal with AI support
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Shortness of breath on exertion? Check for early signs of heart failure
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Ongoing fatigue? AI bot checks if it’s lifestyle or possible cancer fatigue
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Interpret your tumor marker test: Enter CA-125, PSA, or CEA for analysis
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Check your oxygen saturation: Enter SpO2 for AI-guided interpretation
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Back pain checker: Use AI to assess severity and possible causes
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Ankle sprain or fracture? Use AI tool to assess injury severity
Solutions for Smart Healthcare
Clinical Research
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Association of energy source with outcomes in en bloc TURB: secondary analysis of a randomized trial
Study Overview This study evaluates the effectiveness of different energy sources used in a procedure called en-bloc transurethral resection of bladder tumors (ERBT). The goal is to understand how these…
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Exploring therapeutic mechanisms of Chuan Huang Fang-II in the treatment of acute kidney injury on chronic kidney disease patients from the perspective of lipidomics
Exploring Therapeutic Mechanisms of Chuan Huang Fang-II in the Treatment of Acute Kidney Injury on Chronic Kidney Disease Patients Study Information Journal: Ren Fail. 2024 Dec;46(1):2356021 DOI: 10.1080/0886022X.2024.2356021 Date: Epub…
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Efficacy of upadacitinib in subgroups of patients with axial spondyloarthritis with early versus established disease
Study Overview This study looked at how effective a medication called upadacitinib is for patients with axial spondyloarthritis (axSpA), a type of arthritis that affects the spine. The goal was…
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Enhancing Surgical Training: Benefits of Dual-Console vs. Single-Console Systems
Understanding the Trial Results This study looked at two types of training for robotic surgery using the da Vinci Surgical System: dual-console training and single-console training. Here’s what we found:…
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Meet Andesite AI: An Advanced AI Security Analytics Startup that Empowers both Private- and Public-Sector Cyber Experts
Artificial Intelligence (AI) is transforming cybersecurity by addressing the challenges of managing complex threats and overwhelming data. A major obstacle is the shortage of cybersecurity experts, leading to a need…
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Blood Interleukin-18 (IL-18) and IL-18 Binding Protein (IL-18BP) Levels Following Midline Laparotomy: A Prospective Randomized Study of Patients With Benign Disease and Patients With Cancer
“`html Study Title: Blood Interleukin-18 (IL-18) and IL-18 Binding Protein (IL-18BP) Levels Following Midline Laparotomy: A Prospective Randomized Study of Patients With Benign Disease and Patients With Cancer Abstract: Background/Aim:…
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Olaparib in treatment-refractory isocitrate dehydrogenase 1 (IDH1)- and IDH2-mutant cholangiocarcinoma: Safety and antitumor activity from the phase 2 National Cancer Institute 10129 trial
Olaparib for IDH-Mutant Cholangiocarcinoma: Key Findings from a Clinical Trial Background Mutations in isocitrate dehydrogenase (IDH) lead to the buildup of 2-hydroxyglutarate (2-HG), which can promote tumor growth. These mutations…
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Effect of vitamin D in addition to letrozole on the ovulation rate of women with polycystic ovary syndrome: protocol of a multicentre randomised double-blind controlled trial
“`html Effect of Vitamin D and Letrozole on Ovulation in Polycystic Ovary Syndrome Published: BMJ Open, April 29, 2024 Low vitamin D levels are common in women with polycystic ovary…
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Combined oral supplementation with magnesium plus vitamin D alleviates mild to moderate depressive symptoms related to long-COVID: an open-label randomized, controlled clinical trial
Summary of Clinical Trial Findings Study Focus This study investigated how well oral supplements of magnesium and vitamin D can reduce mild to moderate depression symptoms in people suffering from…
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Accuracy of the Wound Healing Questionnaire in the diagnosis of surgical-site infection after abdominal surgery in low- and middle-income countries
Accuracy of the Wound Healing Questionnaire in Diagnosing Surgical Site Infection Practical Solutions and Value Telemedicine is being used for postoperative surveillance, and this study evaluated a telephone Wound Healing…
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Investigating Whether AI Will Replace Human Physicians and Understanding the Interplay of the Source of Consultation, Health-Related Stigma, and Explanations of Diagnoses on Patients’ Evaluations of Medical Consultations: Randomized Factorial Experiment
“`html Understanding AI in Medical Consultations The use of artificial intelligence (AI) in healthcare aims to enhance diagnosis and consultation. However, it’s important to evaluate how this technology affects patients’…
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Effectiveness of high-frequency vibration, cotton rolls and elastomeric wafers in alleviating debonding pain of orthodontic metal brackets: a randomized clinical trial
Effectiveness of Pain Relief Methods During Orthodontic Debonding Study Overview This study examined how effective different methods are in reducing pain during the removal of orthodontic metal brackets. A total…
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Telemedicine for Screening and Follow-Up of Glaucoma: A Descriptive Study
“`html Telemedicine Program for Glaucoma Monitoring Key Findings: Glaucoma affects around 70 million people globally and is expected to impact up to 112 million by 2040. A telemedicine program was…
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Original pericostal suture sparing the neurovascular bundle for prevention of post-thoracotomy pain syndrome after video-assisted mini-thoracotomy
Objective The goal of this study was to prevent pain after thoracic surgery by using a new type of stitching technique that avoids damaging important nerves and blood vessels. Materials…
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Pegylated Liposomal Doxorubicin Combined with Cytarabine and Granulocyte Colony-Stimulating Factor for Treating Newly Diagnosed Older and Unfit Acute Myeloid Leukemia Patients: A Prospective, Single-Center, Single-arm, Phase II Study
Background There are few effective treatments for older patients with acute myeloid leukemia (AML). A study was done to test a new treatment combining pegylated liposomal doxorubicin (PLD), low-dose cytarabine…
