Conditions: Solid Tumor, Adult; BRCA1 Mutation; BRCA2 Mutation; Ovarian Cancer; Breast Cancer; Prostate Cancer
Interventions: Drug: ACE-86225106 tablet
Sponsors: Acerand Therapeutics (Shanghai) Limited
Recruiting
Study of ACE-86225106 to Treat Patients With Advanced Solid Tumors
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Clinical Research
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Effectiveness of Massage Gun Versus Myofascial Release Technique for Releasing Latent Trigger Points of the Calf Muscle: A Protocol for Randomized Clinical Trial
Study Overview This study compares the effectiveness of two treatments for muscle pain in the calf: a massage gun and a myofascial release technique. Both methods aim to relieve pain…
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Predictors and Impact of Disclosure Efficacy Among Cancer Survivors
Predictors and Impact of Disclosure Efficacy Among Cancer Survivors Background Cancer survivors who talk about their diagnosis and experiences gain many benefits, including a better quality of life. Understanding what…
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Capecitabine metronomic chemotherapy for metastatic colorectal cancer patients reaching NED: A protocol for a prospective, randomized, controlled trial
Introduction More patients with metastatic colorectal cancer (mCRC) are now showing no signs of disease after treatment. However, current guidelines don’t clearly recommend ongoing treatment for these patients. Capecitabine metronomic…
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“Enhancing Postoperative Recovery in Cancer Patients: Benefits of Domestic Enteral Nutrition”
Trial Results Explained The study looked at how well a new type of nutrition, called LEOVIT ONCO, helps patients with esophageal and gastric cancer who are not getting enough protein…
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Time-Restricted Eating: No Cardiometabolic Benefits for Women with Overweight
Understanding the Trial Results This study looked at two types of time-restricted eating (TRE) in women with overweight or obesity. The two methods were: Early TRE (eTRE): Eating between 8:00…
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Factorial design study of self-management using Dnurse App in T2DM patients
Background More patients are using diabetes apps on their smartphones to manage their condition. However, there is limited research on the effectiveness of these apps in China. Objective This study…
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Synergistic immunomodulatory effect of synbiotics pre- and postoperative resection of pancreatic ductal adenocarcinoma: a randomized controlled study
“`html Benefits of Synbiotics in Pancreatic Ductal Adenocarcinoma Treatment Synbiotics: A New Approach to Improve PDAC Treatment Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with a low survival…
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The effect of mandala coloring and free coloring on the happiness in veterans with post-traumatic stress disorder in the Covid-19 pandemic: a randomized clinical trial
The Effect of Mandala Coloring on Happiness in Veterans with PTSD during Covid-19 Pandemic Key Findings Art-making, particularly mandala coloring, showed significant improvement in happiness scores among male veterans with…
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Effects of 1-year exercise in patients with atrial fibrillation: study protocol for the Norwegian Exercise in Atrial Fibrillation (NEXAF) randomised controlled trial
Introduction Atrial fibrillation is a common heart rhythm disorder that is expected to rise in the coming years. While lifestyle changes and managing risk factors are important for treatment, there…
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Metabolomic Insights: Anifrolumab’s Impact on Lupus Nephritis Biomarkers
Understanding the Trial Results The trial focused on patients with lupus nephritis, a serious kidney problem caused by lupus, an autoimmune disease. Researchers wanted to see how a treatment called…
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“Enhancing Early Recovery in Robot-Assisted Nephrectomy: The Role of RoSCo Risk Stratification”
Understanding the Trial Results This study looked at a system called RoSCo, designed to help doctors assess the surgical risks for patients before they have robot-assisted kidney surgery for cancer.…
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Anti-dsDNA IgE: a potential non-invasive test for prediction of lupus nephritis relapse
Anti-dsDNA IgE: a Potential Non-Invasive Test for Prediction of Lupus Nephritis Relapse RMD Open. 2024 Jun 28;10(2):e004255. doi: 10.1136/rmdopen-2024-004255. Objectives: The WIN-IgE study aims to assess the value of serum…
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Factors impacting physical activity among post-treatment pediatric cancer survivors with overweight and obesity
Document Factors Affecting Physical Activity in Pediatric Cancer Survivors Published in: Eur J Pediatr. 2024 Apr 26. DOI: 10.1007/s00431-024-05584-6 Abstract Pediatric cancer survivors (PCS) with overweight and obesity are at…
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Evaluation of the effects of occlusal splint and masseter muscle injection in patients with myofascial pain: a randomised controlled trial
Evaluation of Treatments for Myofascial Pain Study Overview This study looked at how effective occlusal splints and muscle injections are for patients with myofascial pain, a common issue in temporomandibular…
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Cardiac arrhythmia assessment with patch electrocardiogram versus insertable cardiac monitor: a cohort study in endurance athletes with atrial fibrillation
Cardiac Arrhythmia Assessment in Endurance Athletes Study Overview This study compared two methods for tracking heart rhythm in endurance athletes with atrial fibrillation (AF). It aimed to evaluate how well…
